DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and FCGR3A

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001121064.2	Gene:	FCGR3A / 2214	HGNCID:	3619	Length:	358	Species:	Homo sapiens

Alignment Length:	300	Identity:	60/300 - (20%)
Similarity:	97/300 - (32%)	Gaps:	92/300 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VPVG-RDALLTCVVH-----------------------DL----VSFKVAWLRV---DTQTILSI 75
            ||:| |.:|:||.:.                       ||    |..:..|.||   |:.| |..
Human    88 VPLGLRISLVTCPLQCGIMWQLLLPTALLLLVSAGMRTDLPKAVVFLEPQWYRVLEKDSVT-LKC 151

  Fly    76 QNHVITKNHRISISHTEHRIWQLK----IRDVQESDRGWYMCQIN----TDPMKSQ--MGYLDVV 130
            |.....:::.....|.|..|....    |......|.|.|.||.|    :||::.:  :|:|.:.
Human   152 QGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQ 216

  Fly   131 VPPDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLT 195
            .|..:.   ..:|.:.       |.|.         :|:......:....:|....:.....:..
Human   217 APRWVF---KEEDPIH-------LRCH---------SWKNTALHKVTYLQNGKGRKYFHHNSDFY 262

  Fly   196 LWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPA- 259
            :.:......|:|.|....|     ||.|            ..:|:.:.:.|.|.:..|:...|.
Human   263 IPKATLKDSGSYFCRGLFG-----SKNV------------SSETVNITITQGLAVSTISSFFPPG 310

  Fly   260 -SVNFWLRDSQL--LQGGSYESVSV----------DHVFR 286
             .|:|.|....|  :..|.|.||..          ||.|:
Human   311 YQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFK 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	29/123 (24%)
		Ig	39..122	CDD:299845	29/118 (25%)
		Ig	132..213	CDD:299845	9/80 (11%)
		IG_like	141..227	CDD:214653	12/85 (14%)
		IG_like	239..322	CDD:214653	16/61 (26%)
		IGc2	245..313	CDD:197706	15/55 (27%)
FCGR3A	NP_001121064.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000