DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and FCGR2B

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_024309811.1	Gene:	FCGR2B / 2213	HGNCID:	3618	Length:	324	Species:	Homo sapiens

Alignment Length:	208	Identity:	42/208 - (20%)
Similarity:	75/208 - (36%)	Gaps:	49/208 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DPKFSGPINNSTVPVGRDALLTC-VVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEH 93
            :|::...:...:|      .||| ..|...|..:.|..                |..:..:||:.
Human    55 EPQWINVLQEDSV------TLTCRGTHSPESDSIQWFH----------------NGNLIPTHTQP 97

  Fly    94 RIWQLKIRDVQESDRGWYMCQIN----TDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTL 154
            . ::.|   ...:|.|.|.||..    :||:...:....:|:....:::|        .|:.:.|
Human    98 S-YRFK---ANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQ--------EGETIVL 150

  Fly   155 TCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTV 219
            .|.         :|:.:....:....:|..:.||....|.::.|...||.|.|.|..:.|.....
Human   151 RCH---------SWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYS 206

  Fly   220 SKRVMLVVNFAPT 232
            ||.|.:.|. ||:
Human   207 SKPVTITVQ-APS 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	18/90 (20%)
		Ig	39..122	CDD:299845	18/87 (21%)
		Ig	132..213	CDD:299845	15/80 (19%)
		IG_like	141..227	CDD:214653	18/85 (21%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
FCGR2B	XP_024309811.1	Ig1_FcgammaR_like	50..128	CDD:143229	19/98 (19%)
FCGR2B	XP_024309811.1	Ig2_FcgammaR_like	132..214	CDD:319307	20/98 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000