DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-iota and FCGR1A

DIOPT Version :9

Sequence 1:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_001365733.1 Gene:FCGR1A / 2209 HGNCID:3613 Length:375 Species:Homo sapiens


Alignment Length:303 Identity:67/303 - (22%)
Similarity:114/303 - (37%) Gaps:76/303 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 VPVGRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQL-------- 98
            |||  |..:......:::.:..|:.|..:..:::...|:   |....|.|:   |.|        
Human    11 VPV--DGQVVDTTKAVITLQPPWVSVFQEETVTLHCEVL---HLPGSSSTQ---WFLNGTATQTS 67

  Fly    99 ----KIRDVQESDRGWYMCQI----NTDPMKSQM--GYLDVVVPPDIVDYQTSQDVVRSTGQNVT 153
                :|.....:|.|.|.||.    .:||::.::  |:|.:         |.|..|. :.|:.:.
Human    68 TPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLL---------QVSSRVF-TEGEPLA 122

  Fly   154 LTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLC-------IA 211
            |.|.|         |:.:....:|...:|....|.....|||:.:...||.|.|.|       ..
Human   123 LRCHA---------WKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYT 178

  Fly   212 SNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITE---SQPA---SVNFWLRDSQL 270
            |.|:..||.:.      |...:.....|..:..|..:||.|.|:   .:|.   ..:|:: .|:.
Human   179 SAGISVTVKEL------FPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYM-GSKT 236

  Fly   271 LQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMG 313
            |:|.:..|     .::|   :|.|   :.|.|.|.|.|....|
Human   237 LRGRNTSS-----EYQI---LTAR---REDSGLYWCEAATEDG 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 20/100 (20%)
Ig 39..122 CDD:299845 20/95 (21%)
Ig 132..213 CDD:299845 19/87 (22%)
IG_like 141..227 CDD:214653 22/92 (24%)
IG_like 239..322 CDD:214653 21/81 (26%)
IGc2 245..313 CDD:197706 19/73 (26%)
FCGR1ANP_001365733.1 Ig1_FcgammaR_like 23..101 CDD:409410 16/83 (19%)
Ig strand B 40..44 CDD:409410 0/3 (0%)
Ig strand C 54..58 CDD:409410 1/6 (17%)
Ig strand E 69..73 CDD:409410 0/3 (0%)
Ig strand F 83..88 CDD:409410 2/4 (50%)
Ig strand G 94..97 CDD:409410 1/2 (50%)
Ig2_FcgammaR_like 105..186 CDD:409411 22/99 (22%)
Ig strand B 121..125 CDD:409411 1/3 (33%)
Ig strand C 135..139 CDD:409411 1/3 (33%)
Ig strand E 152..156 CDD:409411 2/3 (67%)
Ig strand F 166..171 CDD:409411 2/4 (50%)
Ig strand G 179..182 CDD:409411 1/2 (50%)
ig 197..275 CDD:395002 21/84 (25%)
Interaction with EPB41L2. /evidence=ECO:0000269|PubMed:18023480 313..333
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 353..375
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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