Protein Alignment DIP-iota and wrk-1

DIOPT Version :10

• Sequence 1: NP_001097100.1
• Gene: DIP-iota / 33925
• FlyBaseID: FBgn0031837
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001024651.1
• Gene: wrk-1 / 181093
• WormBaseID: WBGene00006942
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 376
• Identity: 76/376 - (20%)
• Similarity: 137/376 - (36%)
• Gaps: 104/376 - (27%)

  Fly    45 GRDALLTCVVHDLVSFKVAWLRVDTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRG 109
            |....|.|.|.| .|..:.| |.:|: ::::.:.::.......|| .|.....|.|:.|:..:..
 Worm    32 GESLTLRCEVED-PSVAIIW-RKNTE-VVAVDDEILDTYGGYEIS-MEGSTSVLTIKRVEPINSA 92

  Fly   110 WYMC---------------------QINTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVT 153
            .|.|                     |::..|:        ||:.||...|.     .|...:|:.
 Worm    93 NYSCALAEPEVSVTFVIKVQVFKPTQVSVKPL--------VVISPDTGVYH-----ARVGEKNLV 144

  Fly   154 LTCSA-TGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASN--GV 215
            :||.. .|.|.|.:.|.::.|.   :.:|..||   ..|..:.:.:|::.|.|.|.|:|.|  |
 Worm   145 ITCHVKEGNPKPGVVWTKQAAK---LPEDIKRE---HGGARIVITEVKKHHAGKYNCLAENIAG- 202

  Fly   216 PPTVSKRVMLVVNFAPTI--------WTRYDTIYVGL--GQKLTLECITESQPASVNFWL----- 265
                |.|..:.::.|..:        |.:.:..::.:  .|..:..|..:..|.....||
 Worm   203 ----SDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYK 263

  Fly   266 ------------RDSQLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRI 318
                        ..:|.|.|.|..:            :|:..|::..||:|.||..|.:|....:
 Worm   264 INFNDEKFKKTSETAQRLNGYSKST------------LTVGDISEEAFGDYACRISNKLGSVTAV 316

  Fly   319 ITVHHKAKKHGQHSHQTSSRESQFI--------VIEEYIANMSDKSCSFQP 361
            :   |.:.:.|  ..|.|..||:..        ::|..:.:..:.:..|.|
 Worm   317 V---HVSGRPG--PPQLSFDESELTWTVRAFDKILEYQLCHRLENADHFLP 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	19/100 (19%)
		Ig strand B	48..52	CDD:143290	1/3 (33%)
		Ig strand C	61..65	CDD:143290	0/3 (0%)
		Ig strand E	96..100	CDD:143290	1/3 (33%)
		Ig strand F	110..115	CDD:143290	2/25 (8%)
		Ig	133..227	CDD:472250	26/96 (27%)
		Ig strand B	152..156	CDD:409562	0/3 (0%)
		Ig strand C	165..169	CDD:409562	0/3 (0%)
		Ig strand E	192..196	CDD:409562	0/3 (0%)
		Ig strand F	206..211	CDD:409562	2/4 (50%)
		Ig strand G	220..223	CDD:409562	1/2 (50%)
		Ig_3	231..310	CDD:464046	17/105 (16%)
wrk-1	NP_001024651.1	IG_like	25..113	CDD:214653	17/84 (20%)
		Ig strand B	35..39	CDD:409353	1/3 (33%)
		Ig strand C	47..51	CDD:409353	1/4 (25%)
		Ig strand E	77..83	CDD:409353	1/5 (20%)
		Ig strand F	93..98	CDD:409353	2/4 (50%)
		Ig strand G	104..107	CDD:409353	0/2 (0%)
		Ig	136..212	CDD:472250	23/86 (27%)
		Ig strand B	143..147	CDD:409353	0/3 (0%)
		Ig strand C	157..161	CDD:409353	0/3 (0%)
		Ig strand E	178..182	CDD:409353	0/3 (0%)
		Ig strand F	192..197	CDD:409353	2/4 (50%)
		Ig	235..319	CDD:472250	18/98 (18%)
		Ig strand C	254..258	CDD:409353	0/3 (0%)
		Ig strand E	278..291	CDD:409353	4/24 (17%)
		Ig strand F	301..306	CDD:409353	2/4 (50%)
		Ig strand G	314..317	CDD:409353	0/2 (0%)