DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-iota and Fcgr2b

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001070657.1	Gene:	Fcgr2b / 14130	MGIID:	95499	Length:	340	Species:	Mus musculus

Alignment Length:	201	Identity:	48/201 - (23%)
Similarity:	72/201 - (35%)	Gaps:	49/201 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LTCVVHDL----VSFKVAWLRV---DTQTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQE-- 105
            |....|||    |..:..|::|   ||.|:      .....|....|.|:   |....|.::.
Mouse    36 LAAGTHDLPKAVVKLEPPWIQVLKEDTVTL------TCEGTHNPGNSSTQ---WFHNGRSIRSQV 91

  Fly   106 ----------SDRGWYMCQIN----TDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTC 156
                      :|.|.|.||:.    :||       :|:.|..|.:..||.| :|...|:.:||.|
Mouse    92 QASYTFKATVNDSGEYRCQMEQTRLSDP-------VDLGVISDWLLLQTPQ-LVFLEGETITLRC 148

  Fly   157 SATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSK 221
            .         :||.:....|....:.....:.....|.::.:...||.|.|.|..|.|.....||
Mouse   149 H---------SWRNKLLNRISFFHNEKSVRYHHYSSNFSIPKANHSHSGDYYCKGSLGRTLHQSK 204

  Fly   222 RVMLVV 227
            .|.:.|
Mouse   205 PVTITV 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	22/97 (23%)
		Ig	39..122	CDD:299845	22/94 (23%)
		Ig	132..213	CDD:299845	18/80 (23%)
		IG_like	141..227	CDD:214653	20/85 (24%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
Fcgr2b	NP_001070657.1	Ig	46..124	CDD:299845	19/93 (20%)
		IG_like	52..110	CDD:214653	13/66 (20%)
		Ig2_FcgammaR_like	128..210	CDD:143230	22/91 (24%)
		IG_like	134..210	CDD:214653	20/85 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000