DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and Fcgr1

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_034316.1	Gene:	Fcgr1 / 14129	MGIID:	95498	Length:	404	Species:	Mus musculus

Alignment Length:	225	Identity:	49/225 - (21%)
Similarity:	87/225 - (38%)	Gaps:	55/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 IRDVQESDRGWYMCQIN----TDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVTLTCSATG 160
            |.:....|.|.|.|||.    :||::.|       :..|.:..|.|:.|: :.|:.:.|.|..
Mouse    82 IPEASFQDSGEYRCQIGSSMPSDPVQLQ-------IHNDWLLLQASRRVL-TEGEPLALRCHG-- 136

  Fly   161 VPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLC-------IASNGVPPT 218
                   |:.:....::...:|....||.:.: :.:.:...||.|.|.|       ..|.||..|
Mouse   137 -------WKNKLVYNVVFYRNGKSFQFSSDSE-VAILKTNLSHSGIYHCSGTGRHRYTSAGVSIT 193

  Fly   219 VSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITE---SQPA---SVNFWLRDSQLLQGGSYE 277
            | |.:........::.:.:..     |..:||.|.|.   .:|.   ..:|:: .|::|:   |.
Mouse   194 V-KELFTTPVLRASVSSPFPE-----GSLVTLNCETNLLLQRPGLQLHFSFYV-GSKILE---YR 248

  Fly   278 SVSVD-HVFRIVMRITLRPITKRDFGEYIC 306
            :.|.: |:.|         ..:.|.|.|.|
Mouse   249 NTSSEYHIAR---------AEREDAGFYWC 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	10/28 (36%)
		Ig	39..122	CDD:299845	9/25 (36%)
		Ig	132..213	CDD:299845	16/87 (18%)
		IG_like	141..227	CDD:214653	20/92 (22%)
		IG_like	239..322	CDD:214653	17/75 (23%)
		IGc2	245..313	CDD:197706	17/69 (25%)
Fcgr1	NP_034316.1	Ig1_FcgammaR_like	32..110	CDD:143229	10/34 (29%)
		IG_like	38..110	CDD:214653	10/34 (29%)
		Ig	114..194	CDD:299845	18/90 (20%)
		IG_like	125..194	CDD:214653	15/78 (19%)
		ig	205..283	CDD:278476	17/83 (20%)
		IG_like	213..271	CDD:214653	17/75 (23%)
		Interaction with EPB41L2. /evidence=ECO:0000250	321..342
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	346..404
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000