DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and FCRLB

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001002901.1	Gene:	FCRLB / 127943	HGNCID:	26431	Length:	426	Species:	Homo sapiens

Alignment Length:	187	Identity:	41/187 - (21%)
Similarity:	75/187 - (40%)	Gaps:	62/187 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 LCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLEC------ITESQPASVNFWLR 266
            |.:.|:|...|:.|.::   :..|. ||   ||:  .|:::||:|      :.|.||.|..::|
Human     9 LLVPSSGQAATLEKPIL---SLHPP-WT---TIF--KGERVTLKCDGYHPLLLELQPISTLWYL- 63

  Fly   267 DSQLLQGGSYESVSVD--HVFR--------------------IVMRITLRPITKRDFGEYI---C 306
             ..||.....:|:.|.  .|:|                    :::::...|:.:   ||.:   |
Human    64 -GHLLLPSHKKSIEVQTPGVYRCQTRGAPVSDPIHLSVSNDWLILQVPYAPVFE---GEPLVLRC 124

  Fly   307 RAKNAMGQTDRIITVHHKAKKHGQHSHQT-----SSRESQFIVIEEYIANMSDKSCS 358
            |     |..|:::     .|.|..|..|.     ||  :.:.|::...::.....||
Human   125 R-----GWYDKVV-----YKLHYYHDGQAVRYFHSS--ANYTVLQARASDSGRYQCS 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653
		Ig	39..122	CDD:299845
		Ig	132..213	CDD:299845	1/4 (25%)
		IG_like	141..227	CDD:214653	5/18 (28%)
		IG_like	239..322	CDD:214653	24/113 (21%)
		IGc2	245..313	CDD:197706	20/98 (20%)
FCRLB	NP_001002901.1	Ig1_FcgammaR_like	23..100	CDD:143229	20/87 (23%)
		Ig2_FcgammaR_like	104..186	CDD:143230	16/81 (20%)
		IG_like	114..190	CDD:214653	15/71 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000