DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and LILRB5

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_011524661.1	Gene:	LILRB5 / 10990	HGNCID:	6609	Length:	670	Species:	Homo sapiens

Alignment Length:	227	Identity:	52/227 - (22%)
Similarity:	83/227 - (36%)	Gaps:	53/227 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 RGWYMCQINTDPMKSQMGYLDVVVP-----PDIVDYQTSQDVVRSTGQNVTLTC-SATGVPMPTI 166
            |.:|..:.|.....:....|:::||     |.::..|.|   |.:.|.::||.| |..|..:..:
Human   194 RCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGS---VVARGGSLTLQCRSDVGYDIFVL 255

  Fly   167 TWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAP 231
               .:|....|:...|.:....:...|.||..|.|||.|.|.|..::.:.|..|         ||
Human   256 ---YKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWS---------AP 308

  Fly   232 TIWTRYDTIYVGL-----------------GQKLTLECITESQPASVNFWLRDS-----QLLQGG 274
            :  ...|.:..||                 |:.:||.|  :|......|:|...     .|....
Human   309 S--DPLDILIAGLIPDIPALSVQPGPKVASGENVTLLC--QSWHQIDTFFLTKEGAAHPPLCLKS 369

  Fly   275 SYESVSVDHVFRIVMRITLRPITKRDFGEYIC 306
            .|:|      :|.....::.|:|....|.|.|
Human   370 KYQS------YRHQAEFSMSPVTSAQGGTYRC 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	3/16 (19%)
		Ig	39..122	CDD:299845	3/13 (23%)
		Ig	132..213	CDD:299845	24/86 (28%)
		IG_like	141..227	CDD:214653	23/86 (27%)
		IG_like	239..322	CDD:214653	18/90 (20%)
		IGc2	245..313	CDD:197706	16/67 (24%)
LILRB5	XP_011524661.1	Ig	27..118	CDD:299845
		Ig	124..217	CDD:299845	4/22 (18%)
		Ig	223..316	CDD:299845	28/109 (26%)
		IG_like	229..>295	CDD:214653	21/71 (30%)
		Ig	324..417	CDD:299845	16/80 (20%)
		IG_like	334..>395	CDD:214653	15/68 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000