DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and pigrl4.2

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001293038.1	Gene:	pigrl4.2 / 105665605	ZFINID:	ZDB-GENE-150409-10	Length:	240	Species:	Danio rerio

Alignment Length:	225	Identity:	54/225 - (24%)
Similarity:	84/225 - (37%)	Gaps:	44/225 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLQSVCFSQASFSELNNSDPKFSGPINNSTVPV--GRDALLTCVVHDLVSF-KVAWLRVDTQ--- 70
            ||.:|.|..|....:...|          .|||  |....:.|:..:.... |..|...:|.
Zfish     6 LLIAVLFCTAGTLSMKTLD----------RVPVIEGETITIPCLYDNKYKLNKKYWCNGNTWLGC 60

  Fly    71 TILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTDPM--KSQMGYLDVVVPP 133
            ::::..||  |....|: .:.:|.::.:.:.:...||.|.|.|.:..|..  .|:..||.|...|
Zfish    61 SVVAYANH--TGKWTIT-DYPDHNMFTVTLNNSTSSDSGHYWCAVEIDHHVDNSKYLYLTVQKAP 122

  Fly   134 DIVDYQTSQDVVRSTGQNVTLTCSATGV---------PMPTITWRREEAT------PILISDDGD 183
            |:  ...|..|....|.:|::.|.....         .:..:|..||:.|      .:.|||||:
Zfish   123 DV--SVLSSSVSGHKGDDVSVRCFYRSAYQNKLKQWCRIDDLTCFREKKTDTSQNSSVQISDDGE 185

  Fly   184 REVFSVEGQNLTLWQVQRSHMGAYLCIASN 213
            .. |:|....|.|     |..|.|.|...|
Zfish   186 SS-FTVLMTGLRL-----SDSGWYFCSVGN 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	20/93 (22%)
		Ig	39..122	CDD:299845	19/90 (21%)
		Ig	132..213	CDD:299845	24/95 (25%)
		IG_like	141..227	CDD:214653	23/88 (26%)
		IG_like	239..322	CDD:214653
		IGc2	245..313	CDD:197706
pigrl4.2	NP_001293038.1	IG_like	26..118	CDD:214653	22/94 (23%)
		Ig_pIgR	30..117	CDD:143193	18/89 (20%)
		Ig	133..217	CDD:299845	21/83 (25%)
		IG_like	136..218	CDD:214653	21/80 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I12510
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000