DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-iota and ntm

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	113/377 - (29%)
Similarity:	172/377 - (45%)	Gaps:	58/377 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLLLQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQTILS 74
            |.|||.|        .:.:.|..|...::|.||..|..|:|.|.|.:.|: :||||  :..|||.
Frog    24 LCLLQGV--------PVRSGDAGFPKAMDNVTVRQGDSAILRCTVDNRVT-RVAWL--NRSTILY 77

  Fly    75 IQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTD--PMKSQMGYLDVVVPPDIVD 137
            ..|...:.:.|:.:.......:.::|::|...|.|.|.|.:.||  |..|:: :|.|.|||.|||
Frog    78 TGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTSRV-HLIVQVPPRIVD 141

  Fly   138 YQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRS 202
            ..:|  :..:.|.||:|.|.|.|.|.|.:.||  ..:|       ....|..|.:.|.:..:.|.
Frog   142 ISSS--IAVNEGSNVSLICIANGRPEPVVNWR--YLSP-------KARGFVSEDEYLEITGITRE 195

  Fly   203 HMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVG--LGQKLTLECITESQPASVNFWL 265
            ..|.|.|.|||.|.....:||.|.||:.|.|   .|...:|  ||.:..|:|...:.||:..||.
Frog   196 QSGIYECSASNDVSAPDVRRVKLTVNYPPYI---LDAQNIGAPLGHRGILQCEASAVPAADFFWY 257

  Fly   266 RDSQLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTDRIITVHHKAKKHGQ 330
            ::.:.| ..|:..|.|:: ...:.|:|...::::|:|.|.|.|||.:|.::..|.:.       :
Frog   258 KEDKRL-SDSWRGVKVEN-RETISRVTFLNVSEQDYGNYTCMAKNLLGHSNASIILF-------E 313

  Fly   331 HSHQTSSRESQFIVIEEYIA--------------NMSDKSCSF-QPLWIMFL 367
            ....|||.    ::.||..|              |.....||| .||.|:.|
Frog   314 LFQSTSSP----LLQEESTAALTPLKGPGAVHDGNSGSTQCSFCAPLLILLL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	28/87 (32%)
		Ig	39..122	CDD:299845	27/84 (32%)
		Ig	132..213	CDD:299845	26/80 (33%)
		IG_like	141..227	CDD:214653	27/85 (32%)
		IG_like	239..322	CDD:214653	24/84 (29%)
		IGc2	245..313	CDD:197706	20/67 (30%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	29/91 (32%)
		IG_like	45..133	CDD:214653	29/91 (32%)
		IG_like	143..220	CDD:214653	27/87 (31%)
		IGc2	150..209	CDD:197706	22/67 (33%)
		ig	227..311	CDD:278476	25/85 (29%)
		IG_like	230..311	CDD:214653	24/82 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm47726
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060