DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-iota and iglon5

DIOPT Version :9

Sequence 1:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	96/313 - (30%)
Similarity:	146/313 - (46%)	Gaps:	35/313 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LPSFWLLLLQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDT 69
            |.|..:::|..|.|.|.:         :|..|.:|.||..|.:|.|:|::.|.|: :||||  :.
Frog    10 LASLGIVMLAQVLFVQCT---------EFVPPADNYTVSQGDNATLSCLIDDKVT-RVAWL--NR 62

  Fly    70 QTILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTD--PMKSQMGYLDVVVP 132
            ..||.......:.:.|:.:.......:.:.|..|..:|.|.|.|...|:  |..||: ||.|.||
Frog    63 SNILYAGKDKWSIDSRVQLLTNTKSEYSIVITHVDVADEGLYTCSFQTEDKPHTSQV-YLIVQVP 126

  Fly   133 PDIVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRREEATPILISDDGDREVFSVEGQNLTLW 197
            ..||:..:|  |..:.|.||.|.|.|.|.|.|||||::..            |.||.||:.|.:.
Frog   127 AKIVNISSS--VTVNEGSNVNLQCLAVGKPEPTITWQQLS------------EGFSSEGELLEIT 177

  Fly   198 QVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVN 262
            ::.|...|.|.|:.||||....:|:|.:.||:.|.| |........:|:..||.|...:.|.:..
Frog   178 EINRQQAGDYECVTSNGVSVPDTKKVQITVNYPPYI-TDVKNAQSPVGRPATLRCKAMAVPPAEF 241

  Fly   263 FWLRDS--QLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMG 313
            .|.:|.  :|:.|....|:..:..:.:   |....:|.|.:|.|.|.|.|.:|
Frog   242 EWYKDEKRRLISGTEGLSIKTESSWSV---IVFSNVTSRHYGNYTCLASNKLG 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	26/87 (30%)
		Ig	39..122	CDD:299845	24/84 (29%)
		Ig	132..213	CDD:299845	28/80 (35%)
		IG_like	141..227	CDD:214653	31/85 (36%)
		IG_like	239..322	CDD:214653	19/77 (25%)
		IGc2	245..313	CDD:197706	18/69 (26%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	29/95 (31%)
		IG_like	35..123	CDD:214653	28/91 (31%)
		Ig	126..207	CDD:299845	34/94 (36%)
		I-set	128..207	CDD:254352	33/92 (36%)
		I-set	210..299	CDD:254352	22/86 (26%)
		Ig	227..298	CDD:143165	18/68 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8421
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.000