DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11050 and HDDC2

DIOPT Version :9

Sequence 1:	NP_609052.1	Gene:	CG11050 / 33924	FlyBaseID:	FBgn0031836	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_057147.2	Gene:	HDDC2 / 51020	HGNCID:	21078	Length:	204	Species:	Homo sapiens

Alignment Length:	202	Identity:	89/202 - (44%)
Similarity:	129/202 - (63%)	Gaps:	2/202 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 ASAGKKPCFSSGLGEILQFMELIGNLKHTKRTGWVLRDVNDCESISGHMYRMSMLTFLLDGSEGL 229
            ||.........|...:|||:.|:|.||...|||||.|:|...||:|.|||||:::..::. .:.|
Human     2 ASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIK-DDRL 65

  Fly   230 NQIRCMELALVHDLAESLVGDITPFCGISKDDKRAMEFKAMEDICKLI-EPRGKRIMELFEEYEH 293
            |:.||:.||||||:||.:||||.|...|.|::|...|.:||:.|.:|: |...|.:.||:||||.
Human    66 NKDRCVRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWEEYET 130

  Fly   294 GQTAESKFVKDLDRLDMVMQAFEYEKRDNCLLKHQEFFDSTEGKFNHPFVKKLVNEIYEQRDVLA 358
            ..:||:||||.||:.:|::||.|||..::...:.|:|:|||.||||||.:.:||:|:..:|....
Human   131 QSSAEAKFVKQLDQCEMILQASEYEDLEHKPGRLQDFYDSTAGKFNHPEIVQLVSELEAERSTNI 195

  Fly   359 KAKGATP 365
            .|..:.|
Human   196 AAAASEP 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11050	NP_609052.1	HD_3	187..323	CDD:289769	65/136 (48%)
HDDC2	NP_057147.2	HD_3	24..183	CDD:289769	76/159 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160121
Domainoid	1	1.000	130	1.000	Domainoid score	I5225
eggNOG	1	0.900	-	-		E1_COG1896
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5431
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4156
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002944
OrthoInspector	1	1.000	-	-		oto89118
orthoMCL	1	0.900	-	-		OOG6_101371
Panther	1	1.100	-	-	LDO	PTHR11845
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3076
SonicParanoid	1	1.000	-	-		X1945
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.780