Protein Alignment Dpp10 and DAP2

DIOPT Version :10

• Sequence 1: NP_001285682.1
• Gene: Dpp10 / 33923
• FlyBaseID: FBgn0031835
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_011893.1
• Gene: DAP2 / 856423
• SGDID: S000001070
• Length: 818
• Species: Saccharomyces cerevisiae
• Alignment Length: 965
• Identity: 238/965 - (24%)
• Similarity: 387/965 - (40%)
• Gaps: 213/965 - (22%)

  Fly     3 EQDNYDDELVSSNPNQRNWRGILIALLVIIIVLALIVTSVVLL---------TPPDEGPRVK--- 55
            |.:...|||..:..     :.:|..|:.:.|:|.|::...|||         ||..:.|...
Yeast     7 EVERIPDELFDTKK-----KHLLDKLIRVGIILVLLIWGTVLLLKSIPHHSNTPDYQEPNSNYTN 66

  Fly    56 -GQ-RIKLQDIVDGLFVPQHSNGSWIDGEEFLYQDHLG-RICLLNAA--------NRSERVLMSN 109
             |: ::....:.:..|.|::....||...:....| || .:..:|.:        :....||:..
Yeast    67 DGKLKVSFSVVRNNTFQPKYHELQWISDNKIESND-LGLYVTFMNDSYVVKSVYDDSYNSVLLEG 130

  Fly   110 VTF----KTLSPFTFTISADKRYLLLAQNVVKLFRHSYLAQYTLYDIQTSESIKLRHSPHQDEWP 170
            .||    :.|:..:.|.|.|.:.||:..|.|:.:|||....|.:||..:|...::.:.
Yeast   131 KTFIHNGQNLTVESITASPDLKRLLIRTNSVQNWRHSTFGSYFVYDKSSSSFEEIGNE------- 188

  Fly   171 YLHYARFTPAGNALVWVQSYDIYYREEVRSASVHRITHDAVPGVVYNGIPDWLYEEEILHANNAI 235
             :..|.::|..|.:.:||..:||....:...::..:|:|. ...::||.|||:||||:...:.|.
Yeast   189 -VALAIWSPNSNDIAYVQDNNIYIYSAISKKTIRAVTNDG-SSFLFNGKPDWVYEEEVFEDDKAA 251

  Fly   236 WMSDNGQLMLYATFNDTHVQEQHFAWYGTTGPSAGGAAAAAAVGAGGAGTGSPGAGGSNPHASLY 300
            |.|..|..:.:...:::.|.|....:|                              ......:|
Yeast   252 WWSPTGDYLAFLKIDESEVGEFIIPYY------------------------------VQDEKDIY 286

  Fly   301 PEIRSLRYPKPGTQNPTVTLRVADLKDPLKVHITDLHPPQIIANEDH---YFSSASWVSHSKIAV 362
            ||:||::|||.||.||...|.|..:||....|      |:|..|:..   ..:..:||.:..:.|
Yeast   287 PEMRSIKYPKSGTPNPHAELWVYSMKDGTSFH------PRISGNKKDGSLLITEVTWVGNGNVLV 345

  Fly   363 VWLNRPQNISVVSVCKAPLFQCIETHRVSGDGRGWVDTVAVPLFAANASI------YVAISPLRD 421
            ...:|..:|..|.:..............|.:|..|..|.......||.:.      ||.|.|:
Yeast   346 KTTDRSSDILTVFLIDTIAKTSNVVRNESSNGGWWEITHNTLFIPANETFDRPHNGYVDILPI-- 408

  Fly   422 GLFGYFRHIVHVD-IDKNRVLPLTHGPYE-VNRLLHWDQLDNWIYFLGTPERLPSQQHLYRVSAL 484
               |.:.|:.:.: .:.:....||.|.:| ||..|.:|.::|.:||:.| .:..:::|:|.:.
Yeast   409 ---GGYNHLAYFENSNSSHYKTLTEGKWEVVNGPLAFDSMENRLYFIST-RKSSTERHVYYID-- 467

  Fly   485 PARQGQALRSPDCLTCPAVSQWSEGYDEGHTKSPPKLVTAWDDDWEDSEEAEAQPPQPALPVEQQ 549
                   ||||:                       :::...|    .||:.
Yeast   468 -------LRSPN-----------------------EIIEVTD----TSEDG-------------- 484

  Fly   550 PPGRGQSAPLPPPPSDCLYHEAKFPISRQAKYVLIDCLGPVVPTSILYGLKSAAADSAKTKRHST 614
                              .::..|...|  ::.|:...||.||...:....|..|:..
Yeast   485 ------------------VYDVSFSSGR--RFGLLTYKGPKVPYQKIVDFHSRKAEKC------- 522

  Fly   615 QQEEPPTEGGDEKPGEEPKSQFLELLVIVQNNTRLKEKMAKTAMPQIKTFPVMISG----GYHAQ 675
                       :|.....||     |..::.|..|.:.:...|:|: |:|..:..|    |....
Yeast   523 -----------DKGNVLGKS-----LYHLEKNEVLTKILEDYAVPR-KSFRELNLGKDEFGKDIL 570

  Fly   676 VRLY--LPPVLREDEITRYPTILHVYSGPGSQLVTDHWHVDWNTYLSGSKDYIVVEIDGRGSAGQ 738
            |..|  ||....|.....||.....|.||.||.|...:.|.:|..::...:.|||.:||||:..:
Yeast   571 VNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIVVVVDGRGTGFK 635

  Fly   739 GYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSRRMGVWGWSYGGYTAALAL---AGQQSIF 800
            |......|..|||..|..||:..:. |..:|.|:|.:::.::|||||||.....|   .|:.  |
Yeast   636 GQDFRSLVRDRLGDYEARDQISAAS-LYGSLTFVDPQKISLFGWSYGGYLTLKTLEKDGGRH--F 697

  Fly   801 QCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSKYVDNLRDRQFLLVHGTADDNVH 865
            :.|:||:|||:|:.|||.|.|||:..|.  :|:.||.||.:.......:..:|||:|||.|||||
Yeast   698 KYGMSVAPVTDWRFYDSVYTERYMHTPQ--ENFDGYVESSVHNVTALAQANRFLLMHGTGDDNVH 760

  Fly   866 VQQSMVLARSLTSKGV-LYKQQIYPDEGHSLSGVKRHLYRSMTAFFEDCFKKLID 919
            .|.|:.....|...|| .|...::||..||:.      |.:....   .|.||:|
Yeast   761 FQNSLKFLDLLDLNGVENYDVHVFPDSDHSIR------YHNANVI---VFDKLLD 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dpp10	NP_001285682.1	DPPIV_N	123..504	CDD:395744	94/391 (24%)
		Peptidase_S9	711..916	CDD:459761	74/208 (36%)
DAP2	NP_011893.1	DPPIV_N	148..508	CDD:395744	103/480 (21%)
		Peptidase_S9	608..815	CDD:459761	77/213 (36%)