Protein Alignment Dpp10 and dpp9

DIOPT Version :10

• Sequence 1: NP_001285682.1
• Gene: Dpp10 / 33923
• FlyBaseID: FBgn0031835
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001070781.2
• Gene: dpp9 / 768170
• ZFINID: ZDB-GENE-061013-777
• Length: 885
• Species: Danio rerio
• Alignment Length: 1020
• Identity: 231/1020 - (22%)
• Similarity: 371/1020 - (36%)
• Gaps: 306/1020 - (30%)

  Fly    55 KGQRIKLQDIVDG-------------------------------LFVPQHSNGSWIDGEEFLYQD 88
            :|:|:||:|..:|                               .||.:|   ||....:.::..
Zfish     3 RGKRVKLEDETEGSWKSFAAVRMTAVDDISDSTEVVEMEDVPSQFFVEKH---SWDGLRDIIHNS 64

  Fly    89 HLGRICLLNAA----------------------------NRSERVLMSNVTFK------------ 113
            .:....::|.|                            :|...:|.|.:..|
Zfish    65 RMYSGMVINKAPHDFQFVQKHDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKIRKEALLVLSWK 129

  Fly   114 -TLSPFTFT----ISADKRYLLLAQNVVKLF---RHSYLAQYTLYDIQTSESI-KLRHSPHQDEW 169
             .|..|..|    :.:.:..||..:..:.:|   .:.|.||..|:..|.|.|: ..|...|..
Zfish   130 QMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDYHAQSGLFLFQASNSLFYCRDGGHNG-- 192

  Fly   170 PYLHYARFTP-------AG------------NALVWVQSYDIYYREEVRSASVHRIT--HDAVPG 213
             ::..|...|       :|            :.:.::.:.|::. ..:.:|...|:|  |..:..
Zfish   193 -FIQAAPMKPMEIKTQCSGIRMDPKISPGDPSFIAFINNNDLWV-TNIETAEERRLTFCHKGLNN 255

  Fly   214 VVYN----GIPDWLYEEEILHANNAIWM------SDNGQL--MLYATFNDTHVQEQHFAWYGTTG 266
            |..:    |:..::.:||........|.      :|.|:.  :||...:::.|:..|.
Zfish   256 VKEDPKSAGVATFVIQEEFDRFTGYWWSPAATEDADGGKTLQLLYEEVDESEVEIIHV------- 313

  Fly   267 PSAGGAAAAAAVGAGGAGTGSPGAGGSNPHASLYPEIRSLRYPKPGTQNPTVTLRVADLKDPLKV 331
                                 |........|.:|      |||:.|::||.::|::|:::
Zfish   314 ---------------------PSPALEERKADVY------RYPRTGSKNPQISLKLAEIR----- 346

  Fly   332 HITDLHPPQIIA-NED------------HYFSSASWVSHSKIA-VVWLNRPQNISVVSVCKAPLF 382
              ||.....|.| |::            .|.:.|.|....|.| .|.|:|.|....:.:....||
Zfish   347 --TDQQGKMISAQNKELVLPFTTLFPGVEYIARAGWTKDGKFAWAVLLDRSQQKLQLVLLPPALF 409

  Fly   383 QCIETHRVSGDGRGWVDTV-AVPLFAANASIYVAISPLRDGLFGYFRHIVHVDIDKNRVLPLTHG 446
                 ..||.|...|.:.| |:|.......||..|:.:...:...|...:....||
Zfish   410 -----IPVSVDDPQWEEHVEAMPEGVQPFIIYEEITDIWINVHDIFYPFIQTSNDK--------- 460

  Fly   447 PYEVNRLLHWDQLDNWIYFLGTPERLPSQQHLYRVSALPARQGQALRSPDCLTCPAVSQWSEGYD 511
                            |.||...|......||||::        :|..|.|      .|||..|
Zfish   461 ----------------ISFLWVNESQTGFCHLYRIT--------SLLKPGC------HQWSREY- 494

  Fly   512 EGHTKSPPKLVTAWDDDWEDSEEAEAQPPQPALPVEQQPPGRGQSAPLPPPPSDCLYHEAKFPIS 576
                 ||.      :||::.|.|.|.     ||.       .|:...|       ..|.:|..::
Zfish   495 -----SPS------EDDFKCSTEEEV-----ALT-------SGEWEVL-------ARHGSKIWVN 529

  Fly   577 RQAKYVLID------------CLGPVVPTSILYGLKSAAADSAKTKR-------HSTQQEEPP-- 620
            .:.|.|...            .:....|..|:...|...:.|....:       |.:....||
Zfish   530 EETKLVYFQGTKDTPLEHHLYVVSYESPGEIVRLTKPGFSHSCSVSQNFDMFISHYSNVSTPPCV 594

  Fly   621 ----TEGGDEKP-GEEPKSQFLELLVIVQNNTRLKEKMAKTAMPQIKTFPVMISGGYHAQVRLYL 680
                ..|.|..| .:||     |....:...|..:.....   |:|.:||.  |.|:.....||.
Zfish   595 HVYKLTGADSDPLHKEP-----EFWASMMEATGCRPDYIP---PEIFSFPA--SSGFRLYGMLYK 649

  Fly   681 PPVLREDEITRYPTILHVYSGPGSQLVTDHW----HVDWNTYLSGSKDYIVVEIDGRGSAGQGYQ 741
            |..|:..:  ::||||.||.||..|||.:.:    ::..||.  .|..|.||.||||||..:|.:
Zfish   650 PHNLKPGK--KHPTILFVYGGPQVQLVNNSYKGVKYLRLNTL--ASLGYAVVVIDGRGSCQRGLK 710

  Fly   742 LLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSRRMGVWGWSYGGYTAALALAGQQSIFQCGISV 806
            ....:..::|.||:.||:|..:::.:...|||..|:.:.||||||:.:.:.|..:.:||:..|:.
Zfish   711 FEGALKNKMGQVEIEDQVEGLQFVAEKYKFIDLSRVAIHGWSYGGFLSLMGLIHRPNIFKVAIAG 775

  Fly   807 SPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSKYVDNL--RDRQFLLVHGTADDNVHVQQS 869
            :|||.|..||:.|.|||:..|.  :|.:|||...::.:||.|  ...:.|::||..|:|||...:
Zfish   776 APVTVWMAYDTGYTERYMDVPE--NNQQGYEAGSVALHVDKLPNEPNRLLILHGFLDENVHFFHT 838

  Fly   870 MVLARSLTSKGVLYKQQIYPDEGHSL----SGVKRHLYRSMTAFF 910
            ..|...|...|..|:.||||:|.||:    ||  .| |..|..:|
Zfish   839 NFLVSQLIRAGKPYQLQIYPNERHSIRCPESG--EH-YEIMLLYF 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dpp10	NP_001285682.1	DPPIV_N	123..504	CDD:395744	82/432 (19%)
		Peptidase_S9	711..916	CDD:459761	75/210 (36%)
dpp9	NP_001070781.2	Dpp_8_9_N	30..158	CDD:466112	16/130 (12%)
		DPPIV_N	171..592	CDD:395744	100/540 (19%)
		Peptidase_S9	684..885	CDD:459761	75/204 (37%)