Protein Alignment CG11319 and DPP8

DIOPT Version :9

• Sequence 1: NP_001285682.1
• Gene: CG11319 / 33923
• FlyBaseID: FBgn0031835
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001307804.1
• Gene: DPP8 / 54878
• HGNCID: 16490
• Length: 898
• Species: Homo sapiens
• Alignment Length: 809
• Identity: 188/809 - (23%)
• Similarity: 295/809 - (36%)
• Gaps: 240/809 - (29%)

  Fly   164 PHQDEW-PYLHYARFTPAGNALVWVQSYDIYYREEVRSASVHRITHDAVPGVVYNGIPDWLYEEE 227
            |...:| .::|        :..:|:.  :|..|||.|...||....:........|:..::.:||
Human   222 PADPDWIAFIH--------SNDIWIS--NIVTREERRLTYVHNELANMEEDARSAGVATFVLQEE 276

  Fly   228 ILHANNAIW------MSDNGQLM--LYATFNDTHVQEQHFAWYGTTGPSAGGAAAAAAVGAGGAG 284
            ....:...|      ....|:::  ||...:::.|:..|     .|.|..
Human   277 FDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIH-----VTSPML--------------- 321

  Fly   285 TGSPGAGGSNPHASLYPEIR---SLRYPKPGTQNPTVTLRVADLKDPLKVHITD------LHPPQ 340
                             |.|   |.||||.||.||.||.:::::....:..|.|      :.|.:
Human   322 -----------------ETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFE 369

  Fly   341 IIANEDHYFSSASWVSHSKIAVVW---LNRPQNISVVSVCKAPLF-----QCIETHRVSGDGRGW 397
            |:.....|.:.|.|....|.|  |   |:|.|....:.:....||     ..:|..|:
Human   370 ILFEGVEYIARAGWTPEGKYA--WSILLDRSQTRLQIVLISPELFIPVEDDVMERQRL------- 425

  Fly   398 VDTV---AVPL--FAANASIYVAISPLRDGLFGYFRHIVHVDIDKNRVLPLTHGPYEVNRLLHWD 457
            :::|   ..||  :.....|::.|           ..|.|       |.|.:|
Human   426 IESVPDSVTPLIIYEETTDIWINI-----------HDIFH-------VFPQSH------------ 460

  Fly   458 QLDNWIYFLGTPERLPSQQHLYRVSAL-----PARQGQALRSPDCLTCP-----AVS--QWS--- 507
              :..|.|:...|.....:|||:::::     ..|....|.:|....||     |::  :|.
Human   461 --EEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLG 523

  Fly   508 -EG------------YDEGHTKSP------------PKLVTAWDDDWEDSEEAEAQPPQPALPVE 547
             .|            |.||...||            |..||...|
Human   524 RHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTD-------------------- 568

  Fly   548 QQPPGRGQSAPLPPPPSDCLYHEAKFPISRQAKYVLIDCLGPVVPTSILYGLKSAAADSAKTKRH 612
                 ||.|      .|.|:.....|.||:.:......|:.       ||.|.|
Human   569 -----RGYS------HSCCISQHCDFFISKYSNQKNPHCVS-------LYKLSS----------- 604

  Fly   613 STQQEEPPTEGGDEKPGEEPKSQFLELLVIVQNNTRLKEKMAKTAMPQIKTFPVMISGGYHAQVR 677
                           |.::|..:..|....:.::.   ..:.....|:|.:|.  .:.|:.....
Human   605 ---------------PEDDPTCKTKEFWATILDSA---GPLPDYTPPEIFSFE--STTGFTLYGM 649

  Fly   678 LYLPPVLREDEITRYPTILHVYSGPGSQLVTDHW----HVDWNTYLSGSKDYIVVEIDGRGSAGQ 738
            ||.|..|:..:  :|||:|.:|.||..|||.:.:    :...||.  .|..|:||.||.|||..:
Human   650 LYKPHDLQPGK--KYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTL--ASLGYVVVVIDNRGSCHR 710

  Fly   739 GYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSRRMGVWGWSYGGYTAALALAGQQSIFQCG 803
            |.:.......::|.:|:.||:|..:||.....|||..|:|:.|||||||.:.:||..:..||:..
Human   711 GLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVA 775

  Fly   804 ISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSKYVDNL--RDRQFLLVHGTADDNVHV 866
            |:.:|||.|..||:.|.|||:..|:  .|.:||....::...:..  ...:.||:||..|:|||.
Human   776 IAGAPVTLWIFYDTGYTERYMGHPD--QNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHF 838

  Fly   867 QQSMVLARSLTSKGVLYKQQIYPDEGHSL 895
            ..:.:|...|...|..|..||||.|.||:
Human   839 AHTSILLSFLVRAGKPYDLQIYPQERHSI 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11319	NP_001285682.1	DPPIV_N	123..504	CDD:279298	74/380 (19%)
		DAP2	<641..916	CDD:224423	87/261 (33%)
		Peptidase_S9	711..916	CDD:278741	69/191 (36%)
DPP8	NP_001307804.1	DPPIV_N	175..595	CDD:395744	93/491 (19%)
		Peptidase_S9	686..891	CDD:395257	69/186 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1506
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810