DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11319 and CG11034

DIOPT Version :9

Sequence 1:	NP_001285682.1	Gene:	CG11319 / 33923	FlyBaseID:	FBgn0031835	Length:	940	Species:	Drosophila melanogaster
Sequence 2:	NP_001285638.1	Gene:	CG11034 / 33810	FlyBaseID:	FBgn0031741	Length:	751	Species:	Drosophila melanogaster

Alignment Length:	849	Identity:	246/849 - (28%)
Similarity:	396/849 - (46%)	Gaps:	174/849 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 NGSWIDGEEFLYQDHLGRICLLNAANRSERVLMSNVTFKTLSPF---TFTISADKRYLLLAQNVV 136
            ||:||.|..:...|.  .|...|||.::: |:..|.:|  |:.:   ||::|.|...:|:..|:.
  Fly    57 NGTWITGTYYTATDR--SIHKFNAATKTD-VIFQNSSF--LNNYVGATFSLSPDNTKILIRHNLT 116

  Fly   137 KLFRHSYLAQYTLYDIQTSESIKLRHSPHQDEWPYLHYARFTPAGN--ALVWVQSYDIYYREEVR 199
            :.|||||:|||.::||:|:.::::    |:.|  .|.|..::|..:  |.|::.:..|::.|.:.
  Fly   117 EKFRHSYIAQYDVFDIETNTTVQI----HKGE--KLQYCGWSPLRDRLAYVYLNNVFIHFSESLE 175

  Fly   200 SASVHRITHDAVPGVVYNGIPDWLYEEEILHANNAIWMSDNGQLMLYATFNDTHVQEQHFAWYGT 264
            .:    ||.|.|.||||||:|||:||||:|.:.:|||.|.:|..:....||||.|:...:..||
  Fly   176 IS----ITDDGVDGVVYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYG- 235

  Fly   265 TGPSAGGAAAAAAVGAGGAGTGSPGAGGSNPHASLYPEIRSLRYPKPGTQNPTVTLRVADLKDPL 329
                            .||.|           ...||....|:|||.|::||.|:|||.|:.|..
  Fly   236 ----------------DGATT-----------FYQYPHEEQLKYPKSGSKNPVVSLRVYDVSDND 273

  Fly   330 KVHITDLHPPQIIANEDHYFSSASWVSHSKIAVVWLNRPQNISVVSVCKAPLFQCIETHRVSGDG 394
            ....|.:.|..|: .:||...|..|.:.:.:.:.|:||.||::.:..|... ..|:|..|:. :.
  Fly   274 PTMHTIVAPVDIV-GDDHILQSVVWSNSTHLLITWMNRRQNLTSIQSCSYE-GDCVEVKRLE-EP 335

  Fly   395 RGWVDTVAVPLFAANASIYVAISPLRDGLFGYF----RHIVHVDIDKNRVLPLTHGPYEVNRLLH 455
            :|||| ::.|         ..:|..:..:||||    ..:.::|::.......:.|.:.|..:..
  Fly   336 QGWVD-ISTP---------KCLSTGKSCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLSVYG 390

  Fly   456 WDQLDNWIYFLGTPERLPSQQHLYRVSALPARQGQALRSPDCLTCPAVSQWSEGYDEGHTKSPPK 520
            :|:..:.:|:..|   ||....:|.|          ..:.:||:|..:
  Fly   391 YDEARDKLYYQAT---LPGDPSVYHV----------FSNDECLSCGQI----------------- 425

  Fly   521 LVTAWDDDWEDSEEAEAQPPQPALPVEQQPPGRGQSAPLPPPPSDCLYHEAKFPISRQAKYVLID 585
                      |::.|..:                               .|....|:...|..:.
  Fly   426 ----------DADGAACR-------------------------------SASGTFSKSFSYYTLS 449

  Fly   586 CLGPVVPTSILYGLKSAAADSAKTKRHSTQQEEPPTEGGDEKPGEEPKSQFLELLVIVQNNTRLK 650
            |.||....:.::        .|.||                           .|.|..:.||..:
  Fly   450 CTGPNPSYTRIF--------EASTK---------------------------TLQVDWEPNTAYR 479

  Fly   651 EKMAKTAMPQIKTFPVMISGGYHAQVRLYLPPVLREDEITRYPTILHVYSGPGSQLVTDHWHVDW 715
            :::.:...|..:...|.::.|.....:|.|||...|.:  :||.|:.||.||.|..||:.:.:.:
  Fly   480 KQIEEKLRPSYRFMNVTLADGSIGYAKLALPPNFVETK--KYPLIVVVYQGPNSVRVTNGFTLGY 542

  Fly   716 NTYLSGSKDYIVVEIDGRGSAGQGYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSRRMGVW 780
            ..:::.|:|.|...|||||:..:|..||..|...||..||.|||.|:.:::.||.|:|:.|.|:|
  Fly   543 EAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAERCGIW 607

  Fly   781 GWSYGGY-TAALALAGQQSIFQCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEESDLSKY 844
            ||||||| ||.........:||||:||:|||:|..||:.|.|||:..|...||.|.|.||.:...
  Fly   608 GWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNESSVFGN 672

  Fly   845 VDNLRDRQFLLVHGTADDNVHVQQSMVLARSLTSKGVLYKQQIYPDEGHSLSGVKRHLYRSMTAF 909
            ::|.:...|||:||:.|||||.|.|::||:.|..:.:.:::|.|.||.|.:.....|||.::.||
  Fly   673 LENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGIGNALPHLYHTIDAF 737

  Fly   910 FEDC 913
            :.:|
  Fly   738 WTNC 741

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11319	NP_001285682.1	DPPIV_N	123..504	CDD:279298	111/386 (29%)
		DAP2	<641..916	CDD:224423	107/274 (39%)
		Peptidase_S9	711..916	CDD:278741	86/204 (42%)
CG11034	NP_001285638.1	DPPIV_N	103..457	CDD:279298	119/475 (25%)
CG11034	NP_001285638.1	Peptidase_S9	538..745	CDD:278741	86/204 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	136	1.000	Domainoid score	I1258
eggNOG	1	0.900	-	-		E1_COG1506
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1947
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D269253at2759
OrthoFinder	1	1.000	-	-		FOG0000419
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100574
Panther	1	1.100	-	-	P	PTHR11731
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X274
	9	8.870