Protein Alignment CG11319 and dpp6

DIOPT Version :9

• Sequence 1: NP_001285682.1
• Gene: CG11319 / 33923
• FlyBaseID: FBgn0031835
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001096462.1
• Gene: dpp6 / 100125080
• XenbaseID: XB-GENE-999312
• Length: 846
• Species: Xenopus tropicalis
• Alignment Length: 941
• Identity: 272/941 - (28%)
• Similarity: 448/941 - (47%)
• Gaps: 165/941 - (17%)

  Fly     2 PEQD-NYDDELVSSNPNQRNWRGILIALLVIIIVLALIVTSVVLLTPPDEGPRVKGQRIKLQDIV 65
            |..| ..:||||.|||.||||:||.||||||:::.:||||||:||||.::.......::.|:|:|
 Frog    56 PRNDCEEEDELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPDEDNSLSLKPKVCLEDLV 120

  Fly    66 DGLFVPQHSNGSWIDGEEFLYQDHLGRICLLNAANRSERVLMSNVTFKTLSPFTFTISADKRYLL 130
            ...|........||:.:..:::...|.:..||.......:|:.|.||:.|....:.:|.|.:|:|
 Frog   121 SRDFAIHDPEAKWINDKTIIFRTQQGNVVKLNVEQNESTLLIENKTFEALKVSKYEVSPDMKYVL 185

  Fly   131 LAQNVVKLFRHSYLAQYTLYDIQTSESIKLRHSPHQDEWPYLHYARFTPAGNALVWVQSYDIYYR 195
            :|.:||.::|.|:.|.|.|.::.|.|...|  :|.:.....|.||.:.|.|..|:::...:|||:
 Frog   186 MAYDVVPVYRRSFTAHYVLCNLITGEHRIL--NPPEVRNAQLQYAGWGPKGQQLIFIFENNIYYQ 248

  Fly   196 EEVRSASVHRITHDAVPGVVYNGIPDWLYEEEILHANNAIWMSDNGQLMLYATFNDTHVQEQHFA 260
            ....|.:: |:......||::||:.|||||||:|..:.|.|.|.:|..:.|:|.|||.|......
 Frog   249 MNAESRAI-RLVSTGKEGVIFNGLSDWLYEEEVLRTHIAHWWSPDGARLAYSTINDTKVPTMEIP 312

  Fly   261 WYGTTGPSAGGAAAAAAVGAGGAGTGSPGAGGSNPHASLYPEIRSLRYPKPGTQNPTVTLRVADL 325
            .|                      ||           ||||.:::..|||.|::||.|||.|.:|
 Frog   313 LY----------------------TG-----------SLYPTVKTYHYPKAGSENPVVTLHVVNL 344

  Fly   326 KDPLKVHITDLHPPQIIANEDHYFSSASWVSHSKIAVVWLNRPQNISVVSVCKAPLFQCIETHRV 390
            ..||  |..::.||......::|.:...|.:.:|:||.||||.||||::::|.|....|.:.|
 Frog   345 NGPL--HHVEMTPPDDQRMREYYITMVKWATSTKVAVNWLNREQNISILTLCDATTGICTKKH-- 405

  Fly   391 SGDGRGWVDTV-AVPLFAANASIYVAISPLRDGLFGYFRHIV----HVDIDKNRVLPLTHGPYEV 450
            ..:...|:... ..|:|:.:...:..:..:..|..|.|.||.    ..:...:.:..:|.|.::|
 Frog   406 EDESEAWLHRQNEEPVFSRDGRKFFFVRAIPQGGRGKFHHIAMSSSQANNSNDNLQSITSGDWDV 470

  Fly   451 NRLLHWDQLDNWIYFLGTPERLPSQQHLYRVSALPARQGQALRSPDCLTCPAVSQWSEGYDEGHT 515
            .::|.:|:.:..:|||.| |..|.::|||..:.    .|...|.  |::|..:..
 Frog   471 TKILAYDEKNQKVYFLST-EDSPRRRHLYSANT----NGSFNRR--CISCDLIEY---------- 518

  Fly   516 KSPPKLVTAWDDDWEDSEEAEAQPPQPALPVEQQPPGRGQSAPLPPPPSDCLYHEAKFPISRQAK 580
                                                              |.|..|.|  |....
 Frog   519 --------------------------------------------------CTYVSASF--SHGLD 531

  Fly   581 YVLIDCLGPVVPTSILYGLKSAAADSAKTKRHSTQQEEPPTEGGDEKPGEEPKSQFLELLVIVQN 645
            |.::.|.||.||...:               |:|...                    ::|:.::|
 Frog   532 YFILRCEGPRVPVVTV---------------HNTTNR--------------------QILIELEN 561

  Fly   646 NTRLKEKMAKTAMPQIKTFPVMISGGYHAQVRLYLPPVLREDEITRYPTILHVYSGPGSQLVTDH 710
            |:.::..|.:..:|.::...:.:. .|...:::..|......  ..||.:|.|...||||.||:.
 Frog   562 NSYVEYAMGEKQIPIVEYTDIQME-DYKLPMQIIKPATFSSK--AHYPLLLVVDGSPGSQSVTER 623

  Fly   711 WHVDWNTYLSGSKDYIVVEIDGRGSAGQGYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFIDSR 775
            :..:|.|.|..|...||.::|||||..||.:|||||.::||.:|..||:|....:... .:||.:
 Frog   624 FQFNWITVLVSSFGAIVAKLDGRGSGFQGTKLLHEVRRKLGFLEEKDQVEALNTMLKK-EYIDKQ 687

  Fly   776 RMGVWGWSYGGYTAALAL-AGQQS-IFQCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYEE 838
            |:||:|..||||.:.|.| :|::: :|.||.::||:|::.||.|.::||||..  .|.:.:.||.
 Frog   688 RVGVFGKDYGGYLSTLLLTSGEENPLFSCGAALSPITDFSLYASAFSERYLGL--YTADNRAYEL 750

  Fly   839 SDLSKYVDNLRDRQFLLVHGTADDNVHVQQSMVLARSLTSKGVLYKQQIYPDEGHSL--SGVKRH 901
            :.|::....|:..:||::|.|||:.||.|.:..|.:.|..:...|...|||||.|.:  ..:::|
 Frog   751 AKLARRASALKKGKFLIIHATADEKVHFQHTADLIKHLVKENANYSLLIYPDESHYMRSEAMEKH 815

  Fly   902 LYRSMTAFFEDCFK-----KLIDQQQQNQTD 927
            |::|:.:|||:||:     .:::..::.:.|
 Frog   816 LHKSIVSFFEECFRIQDRPPVVEIDEEEEED 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11319	NP_001285682.1	DPPIV_N	123..504	CDD:279298	115/385 (30%)
		DAP2	<641..916	CDD:224423	97/283 (34%)
		Peptidase_S9	711..916	CDD:278741	81/213 (38%)
dpp6	NP_001096462.1	DPPIV_N	178..543	CDD:279298	124/473 (26%)
		Abhydrolase	624..831	CDD:304388	81/209 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	189	1.000	Domainoid score	I3226
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	445	1.000	Inparanoid score	I1595
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D269253at2759
OrthoFinder	1	1.000	-	-		FOG0000419
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11731
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X274
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.070