Protein Alignment Dpp10 and dpp6a

DIOPT Version :10

• Sequence 1: NP_001285682.1
• Gene: Dpp10 / 33923
• FlyBaseID: FBgn0031835
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: XP_009295542.2
• Gene: dpp6a / 100007104
• ZFINID: ZDB-GENE-090918-4
• Length: 810
• Species: Danio rerio
• Alignment Length: 925
• Identity: 278/925 - (30%)
• Similarity: 428/925 - (46%)
• Gaps: 181/925 - (19%)

  Fly    10 ELVSSNPNQRNWRGILIALLVIIIVLALIVTSVVLLTPPDEGPRVKGQRIKLQDIVDGLFVPQHS 74
            |||.|||.||||:||.||||||:::.:||||||:||||.::......:::.:::|....|.....
Zfish    30 ELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPGEDDSLAFKEKVTVEEIFKKDFKVHDP 94

  Fly    75 NGSWIDGEEFLYQDHLGRICLLNAANRSERVLMSNVTFKTLSPFTFTISADKRYLLLAQNVVKLF 139
            |..||...|.||:...|.:...|.......:|::|..|:......:.:|.|.:.:|||.||..::
Zfish    95 NAKWISNNELLYRTREGDVVRFNMETNESTILVTNRKFEMYKASKYEVSPDMKLVLLAYNVQLVY 159

  Fly   140 RHSYLAQYTLYDIQTSESIKLRHSPHQDEWPYLHYARFTPAGNALVWVQSYDIYYREEVRSASVH 204
            .||:.|.|.:..::|.|:..|  :|.:....:|.||.:.|.|..|:::...:||||..|.:.|:
Zfish   160 EHSFTADYIICSLETPETWIL--NPPEVRNAHLQYAGWGPRGQQLIFIFENNIYYRATVENRSI- 221

  Fly   205 RITHDAVPGVVYNGIPDWLYEEEILHANNAIWMSDNGQLMLYATFNDTHVQEQHFAWYGTTGPSA 269
            |:......||::||:.|||||.||..::.|.|.|.:|..:.|||.|||.|.......:
Zfish   222 RLVSTGKEGVIFNGLTDWLYEAEIFKSHIAHWWSPDGARLAYATINDTLVPRMEIPMF------- 279

  Fly   270 GGAAAAAAVGAGGAGTGSPGAGGSNPHASLYPEIRSLRYPKPGTQNPTVTLRVADLKDPLKVHIT 334
                           ||           ||||..|...|||.|.:||.::|.|.:|..||  |..
Zfish   280 ---------------TG-----------SLYPTARQYHYPKAGEENPIISLYVVNLNGPL--HTI 316

  Fly   335 DLHPPQIIANEDHYFSSASWVSHSKIAVVWLNRPQNISVVSVCKAPLFQCIETHRVSGDGRGWVD 399
            ::..|:.....::|.:...|.:.:|:||.||||.||||::::|.|....|.:.|  ..:..||:.
Zfish   317 EMRRPEDQRIGEYYVTMVKWATSTKLAVNWLNRAQNISILTLCVATTGVCTKKH--EDESEGWLH 379

  Fly   400 TV-AVPLFAANASIYVAISPLRDGLFGYFRHIV---------HVDI-------DKNRVLPLTHGP 447
            .. ..|||:            :|||..:|...:         |:.:       ..:.:..:|.|.
Zfish   380 RQNEEPLFS------------KDGLRLFFTRAIPQGGRGKFFHISMSISQPNSSTDTLQSITSGD 432

  Fly   448 YEVNRLLHWDQLDNWIYFLGTPERLPSQQHLYRVSALPARQGQALRSPDCLTCPAVSQWSEGYDE 512
            ::|.::|.:|:....||||.| |..|.::|||....:    |...|.  ||:|
Zfish   433 WDVTQVLAYDEESQLIYFLST-EDDPKRRHLYSADTV----GTFNRR--CLSC------------ 478

  Fly   513 GHTKSPPKLVTAWDDDWEDSEEAEAQPPQPALPVEQQPPGRGQSAPLPPPPSDCLYHEAKFPISR 577
                           |:.||                                 |.|....|  |.
Zfish   479 ---------------DFTDS---------------------------------CGYVSGSF--SP 493

  Fly   578 QAKYVLIDCLGPVVPTSILYGLKSAAADSAKTKRHSTQQEEPPTEGGDEKPGEEPKSQFLELLVI 642
            ...|.|::|.||.||.:.:|               ||...:              |.|.:||
Zfish   494 TMDYFLLNCKGPGVPYAAVY---------------STHDRQ--------------KVQDIEL--- 526

  Fly   643 VQNNTRLKEKMAKTAMPQIKTFPVMISGGYHAQVRLYLPPVLREDEITRYPTILHVYSGPGSQLV 707
               |..|:.|:....||:::...:.|. .|...|::..|...  .:.:.||.:|.|...||||.|
Zfish   527 ---NLNLRRKVNSMQMPRVEYREINIE-DYSLSVQILKPAGF--IDTSHYPLLLLVDGTPGSQSV 585

  Fly   708 TDHWHVDWNTYLSGSKDYIVVEIDGRGSAGQGYQLLHEVYKRLGSVEVSDQLEVSEYLRDNLHFI 772
            ::.:|:||.:.|..|...:.|..|||||..||..|||:|.:|||..|..|||:|...:... .:|
Zfish   586 SEQFHIDWASVLVSSFGVVAVRFDGRGSGFQGTNLLHKVQRRLGMFEEKDQLDVLSIMMQE-PYI 649

  Fly   773 DSRRMGVWGWSYGGYTAALALAGQQSIFQCGISVSPVTNWKLYDSTYAERYLSFPNVTDNYKGYE 837
            |..|:|.:|..||||..:|.|:.:.|:.:|...:||:|::.||.|.::||||..|.  .:.:.||
Zfish   650 DKTRIGAFGQVYGGYITSLLLSSEDSMLKCAAVLSPITDFALYASAFSERYLGPPK--PDRRAYE 712

  Fly   838 ESDLSKYVDNLRDRQFLLVHGTADDNVHVQQSMVLARSLTSKGVLYKQQIYPDEGHSLSG--VKR 900
            .::|:.......|::||::|.|||:.||.|.:......|.|:...|..||||||||.:..  .::
Zfish   713 MANLAYRASQFIDKKFLIIHPTADEKVHFQHTAKFISRLISERANYSLQIYPDEGHFIHNELTRQ 777

  Fly   901 HLYRSMTAFFEDCFK 915
            ||.:|:..|||:||:
Zfish   778 HLSQSLVNFFEECFR 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dpp10	NP_001285682.1	DPPIV_N	123..504	CDD:395744	117/397 (29%)
		Peptidase_S9	711..916	CDD:459761	81/207 (39%)
dpp6a	XP_009295542.2	None