Protein Alignment Ent2 and FUN26

DIOPT Version :10

• Sequence 1: NP_609049.1
• Gene: Ent2 / 33921
• FlyBaseID: FBgn0263916
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_009380.1
• Gene: FUN26 / 851211
• SGDID: S000000020
• Length: 517
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 121/533 - (22%)
• Similarity: 209/533 - (39%)
• Gaps: 118/533 - (22%)

  Fly     1 MAEAKSEKSPFIGKQQAPVTLNPSWESKLPPH-DSNGKG--------STSVLAKLGLPAPKDKFL 56
            :|:..||:....|::.         ||:...| |..|..        ||..|..  ||..|....
Yeast    22 LADTHSEEISRSGEEH---------ESENNEHSDEEGDNYSEREQSVSTEPLDT--LPLRKKLKN 75

  Fly    57 IVFFIFLLHGVGTLMPWNMFITAKSYFED--FKFGPNNTVATEVSYRTHFMQNMGFASQIPNLVF 119
            :.:..|...|:|.|.|||..::|..||:.  ||   :.::..::     |..:|...|.|.:::|
Yeast    76 LSYITFFAIGIGLLWPWNCILSASQYFKHDIFK---DTSIWAKI-----FTSSMMSFSTISSMLF 132

  Fly   120 NWLNIFV-----NFGGDLTTRIVYSIIFEMVILLVTIILAMLDSSQWPGVFFWTTMVCIVLLNVC 179
               ||::     .:...:...:|:.||...|:...||:..:|  .:|....|  .|:.:|:.::.
Yeast   133 ---NIYLAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLL--PKWFNFMF--IMMLVVISSMG 190

  Fly   180 NGIYQNTIYGIVASLPIKYTGAVVLGSNISGCFTT----AMALICGEIFSSKRTSAI-YYFVTAI 239
            ..:.||.|..|......:|:..|::|..::|...:    |:|.|  |..|...|..| .||.|..
Yeast   191 TAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFI--ENSSVSTTGGILLYFFTTT 253

  Fly   240 LVLLLCFDTYFALPLNKFFR-----------------------------------------HYET 263
            ||:.:|...:   .::|..|                                         |..|
Yeast   254 LVVTICVVMF---SVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRT 315

  Fly   264 ISRSSEKKSDSKAQLNVPYWQIFKKAAPQLFNIFLTFFVTLSVFPAIQSNVHRSDPNFVVG---- 324
            .....:.....:.||.||:..:|.|....:.:||.||.||| |||...|      ..:|.|
Yeast   316 NGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTL-VFPVFAS------ATYVTGLPLS 373

  Fly   325 -PDYFTLVTCFATFNVFAMLGSLTTSWVQWPG----PRFLWVPVVLRLAFIPLFVMCNYVPP--- 381
             ..|..|:  |..:|:..:.|.:...|..:..    ||..::..:||:|.||||:|...:..
Yeast   374 NAQYIPLI--FTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSS 436

  Fly   382 -DSVRSLAVFIENDWVYWGIGIAMAYSSGYLSSLGMMYAPQTV-HTKYQTTAGMYAAAMLITGIF 444
             |...:.:|.:  |..|..:......::|::.|:..|..|:.: :...:..||.:....:.||:.
Yeast   437 GDEEHNGSVIV--DLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLA 499

  Fly   445 SGVLFSYLGPFFV 457
            .|.:.||:..|.:
Yeast   500 LGSIISYVFVFII 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ent2	NP_609049.1	Nucleoside_tran	62..457	CDD:472807	106/461 (23%)
FUN26	NP_009380.1	2a57	81..514	CDD:273352	106/463 (23%)