Protein Alignment Ent2 and FUN26

DIOPT Version :9

• Sequence 1: NP_001285680.1
• Gene: Ent2 / 33921
• FlyBaseID: FBgn0263916
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_009380.1
• Gene: FUN26 / 851211
• SGDID: S000000020
• Length: 517
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 121/533 - (22%)
• Similarity: 209/533 - (39%)
• Gaps: 118/533 - (22%)

  Fly     1 MAEAKSEKSPFIGKQQAPVTLNPSWESKLPPH-DSNGKG--------STSVLAKLGLPAPKDKFL 56
            :|:..||:....|::.         ||:...| |..|..        ||..|..  ||..|....
Yeast    22 LADTHSEEISRSGEEH---------ESENNEHSDEEGDNYSEREQSVSTEPLDT--LPLRKKLKN 75

  Fly    57 IVFFIFLLHGVGTLMPWNMFITAKSYFED--FKFGPNNTVATEVSYRTHFMQNMGFASQIPNLVF 119
            :.:..|...|:|.|.|||..::|..||:.  ||   :.::..::     |..:|...|.|.:::|
Yeast    76 LSYITFFAIGIGLLWPWNCILSASQYFKHDIFK---DTSIWAKI-----FTSSMMSFSTISSMLF 132

  Fly   120 NWLNIFV-----NFGGDLTTRIVYSIIFEMVILLVTIILAMLDSSQWPGVFFWTTMVCIVLLNVC 179
               ||::     .:...:...:|:.||...|:...||:..:|  .:|....|  .|:.:|:.::.
Yeast   133 ---NIYLAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLL--PKWFNFMF--IMMLVVISSMG 190

  Fly   180 NGIYQNTIYGIVASLPIKYTGAVVLGSNISGCFTT----AMALICGEIFSSKRTSAI-YYFVTAI 239
            ..:.||.|..|......:|:..|::|..::|...:    |:|.|  |..|...|..| .||.|..
Yeast   191 TAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFI--ENSSVSTTGGILLYFFTTT 253

  Fly   240 LVLLLCFDTYFALPLNKFFR-----------------------------------------HYET 263
            ||:.:|...:   .::|..|                                         |..|
Yeast   254 LVVTICVVMF---SVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRT 315

  Fly   264 ISRSSEKKSDSKAQLNVPYWQIFKKAAPQLFNIFLTFFVTLSVFPAIQSNVHRSDPNFVVG---- 324
            .....:.....:.||.||:..:|.|....:.:||.||.||| |||...|      ..:|.|
Yeast   316 NGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTL-VFPVFAS------ATYVTGLPLS 373

  Fly   325 -PDYFTLVTCFATFNVFAMLGSLTTSWVQWPG----PRFLWVPVVLRLAFIPLFVMCNYVPP--- 381
             ..|..|:  |..:|:..:.|.:...|..:..    ||..::..:||:|.||||:|...:..
Yeast   374 NAQYIPLI--FTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSS 436

  Fly   382 -DSVRSLAVFIENDWVYWGIGIAMAYSSGYLSSLGMMYAPQTV-HTKYQTTAGMYAAAMLITGIF 444
             |...:.:|.:  |..|..:......::|::.|:..|..|:.: :...:..||.:....:.||:.
Yeast   437 GDEEHNGSVIV--DLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLA 499

  Fly   445 SGVLFSYLGPFFV 457
            .|.:.||:..|.:
Yeast   500 LGSIISYVFVFII 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ent2	NP_001285680.1	Nucleoside_tran	62..457	CDD:301621	106/461 (23%)
FUN26	NP_009380.1	2a57	81..514	CDD:273352	106/463 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343786
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1479
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3732
OMA	1	1.010	-	-		QHG53699
OrthoFinder	1	1.000	-	-		FOG0000541
OrthoInspector	1	1.000	-	-		otm46784
orthoMCL	1	0.900	-	-		OOG6_100863
Panther	1	1.100	-	-	O	PTHR10332
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2123
SonicParanoid	1	1.000	-	-		X296
TreeFam	1	0.960	-	-
	13	12.690