Protein Alignment Ent2 and SLC29A4

DIOPT Version :9

• Sequence 1: NP_001285680.1
• Gene: Ent2 / 33921
• FlyBaseID: FBgn0263916
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_001035751.1
• Gene: SLC29A4 / 222962
• HGNCID: 23097
• Length: 530
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 109/480 - (22%)
• Similarity: 188/480 - (39%)
• Gaps: 114/480 - (23%)

  Fly    49 PAPKDKFLIVFFIFLLHGVGTLMPWNMFITAKSYFEDFKFGPNNTVATEVSYRTHFMQNMGFASQ 113
            |.|.|::..::|..||.|||.|:|:|.|||...|.. .|: |..::..::|. |:.:..:. |..
Human    61 PVPDDRYHAIYFAMLLAGVGFLLPYNSFITDVDYLH-HKY-PGTSIVFDMSL-TYILVALA-AVL 121

  Fly   114 IPNLVFNWLNIFVNFGGDLTTRIVYSIIFEMVILLVTIILAMLDSSQWPGVFFWTTMVCIVLLNV 178
            :.|::...|.        |.|||....:..:..||...|..:     |..:|.......|.|..|
Human   122 LNNVLVERLT--------LHTRITAGYLLALGPLLFISICDV-----WLQLFSRDQAYAINLAAV 173

  Fly   179 ------CNGIYQNTIYGIVASLPIKYTGAVVLGSNISGCFTTAMALICGEIFSSKRTSAIYYFVT 237
                  |. :.|::.||....||.:||..|:.|.:.:|...:...::...:...:|.|.:.:|:.
Human   174 GTVAFGCT-VQQSSFYGYTGMLPKRYTQGVMTGESTAGVMISLSRILTKLLLPDERASTLIFFLV 237

  Fly   238 AILVLLLCFDTYFALPLNKFFRHYETISRSS---------------------------------- 268
            ::.:.||||..:..:..::|...|.|..|.|
Human   238 SVALELLCFLLHLLVRRSRFVLFYTTRPRDSHRGRPGLGRGYGYRVHHDVVAGDVHFEHPAPALA 302

  Fly   269 --EKKSDSKA-----------QLNVP------YWQIFKKAA-----------PQLFNIFLTFFVT 303
              |...||.|           :.:||      .|..|:...           ..:.:|.:|:|:|
Human   303 PNESPKDSPAHEVTGSGGAYMRFDVPRPRVQRSWPTFRALLLHRYVVARVIWADMLSIAVTYFIT 367

  Fly   304 LSVFPAIQSNVHRSDPNFVVGPDYFTLVTCFATFNVFAMLGSLTTSW-VQWPGPRFLWVPVVLRL 367
            |.:||.::|.:.    :.::|.  :..:...|.||:...:|.:..:. |.|.|...| ....||:
Human   368 LCLFPGLESEIR----HCILGE--WLPILIMAVFNLSDFVGKILAALPVDWRGTHLL-ACSCLRV 425

  Fly   368 AFIPLFVMCNYVPPDSVRSL------AVFIENDWVYWGIGIAMAYSSGYLSSLGMMYAPQTVHTK 426
            .|||||::|.|  |..:.:|      .:|          .:.|..|:||..|:.|:.|...|..|
Human   426 VFIPLFILCVY--PSGMPALRHPAWPCIF----------SLLMGISNGYFGSVPMILAAGKVSPK 478

  Fly   427 YQTTAGMYAAAMLITGIFSGVLFSY 451
            .:..||.......::|:..|...:|
Human   479 QRELAGNTMTVSYMSGLTLGSAVAY 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ent2	NP_001285680.1	Nucleoside_tran	62..457	CDD:301621	105/467 (22%)
SLC29A4	NP_001035751.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Nucleoside_tran	75..503	CDD:301621	104/464 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1479
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53699
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820