Protein Alignment Ent2 and ent-2

DIOPT Version :9

• Sequence 1: NP_001285680.1
• Gene: Ent2 / 33921
• FlyBaseID: FBgn0263916
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_510571.1
• Gene: ent-2 / 181648
• WormBaseID: WBGene00010701
• Length: 450
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 174/458 - (37%)
• Similarity: 260/458 - (56%)
• Gaps: 29/458 - (6%)

  Fly    17 APVTLNPSWESKLPPHDSNGKGSTSVLAKLGLPAPKDKFLIVFFIFLLHGVGTLMPWNMFIT-AK 80
            |.|.|.|..|:| ...|:..:..|        |.|:||..:||:|.||||:||||||||.|| :.
 Worm     3 AAVELQPLNEAK-KVEDAEVEEET--------PEPEDKGNLVFYIILLHGIGTLMPWNMLITISY 58

  Fly    81 SYFEDFKFGPNNTVATEVS--------YRTHFMQNMGFASQIPNLVFNWLNIFVNFGGDLTTRIV 137
            .|||.:|...|:|:..:..        |.::|......|||:|||:.|.||||:...|.|..||.
 Worm    59 DYFESYKMLANSTIDMDTGKVTGDPTVYSSNFQSFQTIASQVPNLLLNLLNIFIVVKGGLAGRIT 123

  Fly   138 YSIIFEMVILLVTIILAMLDSSQWPGVFFWTTMVCIVLLNVCNGIYQNTIYGIVASLPIKYTGAV 202
            ..:....|.::.|:|...:::|.|...||..|::.|::||..||:|||:|:|:.:.||.|||.||
 Worm   124 VGLSIVAVCVITTMIFIYVETSTWLTGFFTLTIITIIVLNGANGVYQNSIFGLASELPFKYTNAV 188

  Fly   203 VLGSNISGCFTTAMALICGEIFSSKRTSAIYYFVTAILVLLLCFDTYFALPLNKFFRHYETISR- 266
            ::|:|:.|.|.|.:::....:..:....:..||..|::.|:.||.::..|...:|::.|.|.:.
 Worm   189 IIGNNLCGTFVTLLSMSTKAVTRNILDRSFAYFSIALITLVFCFISFHILKKQRFYQFYSTRAER 253

  Fly   267 ---SSEKKSDSKAQLNVPYWQIFKKAAPQLFNIFLTFFVTLSVFPAIQSNVHRSDP----NFVVG 324
               .:|:.:|::.:: ..|...||:|.|||.|:||.||||||:||.:...|.....    :|.:.
 Worm   254 QRAKNEEAADNEGKM-ANYIATFKEAFPQLINVFLVFFVTLSIFPGVMMYVKDEKKGGTYDFPLP 317

  Fly   325 PDYFTLVTCFATFNVFAMLGSLTTSWVQWPGPRFLWVPVVLRLAFIPLFVMCNYVPPDSVRSLAV 389
            .:||..||.|..|||||.:||:.....|||.|..||:||.|||.:||.|:.|||:|  ..|:|.|
 Worm   318 QNYFMDVTTFLQFNVFAFIGSIVAGRKQWPAPNKLWIPVYLRLLYIPFFIFCNYLP--ETRTLPV 380

  Fly   390 FIENDWVYWGIGIAMAYSSGYLSSLGMMYAPQTVHTKYQTTAGMYAAAMLITGIFSGVLFSYLGP 454
            |.|:.|::..:..:|::.|||.|.|.|||..:||.......|||.|...||:||.||::|:.:..
 Worm   381 FFESTWLFIIVAASMSFGSGYFSGLSMMYTSKTVDPSKAQVAGMMAGFFLISGIVSGLIFTMVIK 445

  Fly   455 FFV 457
            |.|
 Worm   446 FVV 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ent2	NP_001285680.1	Nucleoside_tran	62..457	CDD:301621	158/411 (38%)
ent-2	NP_510571.1	Nucleoside_tran	156..446	CDD:301621	112/292 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159265
Domainoid	1	1.000	226	1.000	Domainoid score	I1433
eggNOG	1	0.900	-	-		E1_KOG1479
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H130957
Inparanoid	1	1.050	318	1.000	Inparanoid score	I1507
Isobase	1	0.950	-	0	Normalized mean entropy	S3732
OMA	1	1.010	-	-		QHG53699
OrthoDB	1	1.010	-	-		D318009at33208
OrthoFinder	1	1.000	-	-		FOG0000541
OrthoInspector	1	1.000	-	-		otm14143
orthoMCL	1	0.900	-	-		OOG6_100863
Panther	1	1.100	-	-	LDO	PTHR10332
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2123
SonicParanoid	1	1.000	-	-		X296
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790