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Protein Alignment Trmt6 and TRMT6

DIOPT Version :10

Sequence 1:	NP_609048.2	Gene:	Trmt6 / 33920	FlyBaseID:	FBgn0031832	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_057023.2	Gene:	TRMT6 / 51605	HGNCID:	20900	Length:	497	Species:	Homo sapiens

Alignment Length:	474	Identity:	139/474 - (29%)
Similarity:	243/474 - (51%)	Gaps:	72/474 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RIQLGDYIVIQRQ---KYTKLQKFGSLDTTATLGKETLELKSLLDQPYGSTFKMCVKETKPGKRG 70
            ||:.||::|::|:   |..::|:    ....|..|:...|.:::...||:.|::    |..|...
Human    19 RIRDGDFVVLKREDVFKAVQVQR----RKKVTFEKQWFYLDNVIGHSYGTAFEV----TSGGSLQ 75

  Fly    71 AQRQHTLELCSETELRSTREVLGISSSGADNRDIRDDGEAQTLKPEDIAQLREECNDSSKIIEKL 135
            .:::.      |.....|:|      :|.|||:|.|||::|.|..:||..|:::.....:|:::|
Human    76 PKKKR------EEPTAETKE------AGTDNRNIVDDGKSQKLTQDDIKALKDKGIKGEEIVQQL 128

  Fly   136 VENSKTFHNRTEYSQEKYLLKKEKKYFEFVQIRQPTIRLMLDIFYRQDSEKVMGIRVDTLSQIIS 200
            :|||.||.::||::|:||:.||:|||...:.:.:|:.|::..::|.::..|:..:|.|||:|:::
Human   129 IENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMYYAREPGKINHMRYDTLAQMLT 193

  Fly   201 YSGVCGFGSYLLYESGTNGLLPAAMLNSIGAGTEGTLVHMHPGNVPQKQALSALKLPLEQQQRCV 265
            ...:.. |:.::......||:..||:..:|.  .|:::.::||..|.:.|.:....|     :..
Human   194 LGNIRA-GNKMIVMETCAGLVLGAMMERMGG--FGSIIQLYPGGGPVRAATACFGFP-----KSF 250

  Fly   266 SVNLY--------SVLREFYQGG--DAKATDIPVVE----------PSENEPQETQLETPTEEQP 310
            ...||        |:|...:...  .::..|..:||          .||.|.:::..|.|....|
Human   251 LSGLYEFPLNKVDSLLHGTFSAKMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHP 315

  Fly   311 E--------AIEPTTKKPK--------LDESNSGREGAKGPPRWHLENKRATALMHAEFDSLVVA 359
            |        :.:|..|.||        :.|....:|..:   :.|||  .|..|.....|.|:||
Human   316 EDQETMETISQDPEHKGPKERGSKKDYIQEKQRRQEEQR---KRHLE--AAALLSERNADGLIVA 375

  Fly   360 AKEHPSNILQALLPLVKPSRPVVVFSTCKELLQETFMELKTTGKVTGLHLTSNWLRTYQILPNRT 424
            ::.||:.:|.:||..|.||||.||:...||.|.|.:.:|:..|.|..|.|:..|||.||:||:|:
Human   376 SRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRS 440

  Fly   425 HPEVNMSGNSGYLLTGYTL 443
            ||::.|||..||||:|:|:
Human   441 HPKLLMSGGGGYLLSGFTV 459

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.