Protein Alignment IFT52 and osm-6

DIOPT Version :9

• Sequence 1: NP_609045.2
• Gene: IFT52 / 33917
• FlyBaseID: FBgn0031829
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_741633.1
• Gene: osm-6 / 179631
• WormBaseID: WBGene00003886
• Length: 472
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 124/433 - (28%)
• Similarity: 225/433 - (51%)
• Gaps: 34/433 - (7%)

  Fly     7 ICFDTSKNERFQISDNYKMMHRKLKVNWNVEQNDAELRMERLARVKIFVLAGPQDRFTEDEFDVL 71
            :..|.||.::..:...::.:.|.||....||.|...:.:..|..|::.::..|:..|...|.:.:
 Worm    18 VLIDQSKQQQISLISGFRGVARHLKSVLTVEINTEPINLNGLEDVRMLIIPQPKTSFGTGEIEAI 82

  Fly    72 KHYVEVQGGSLVVLLGEGGEPEFNTNVNFFLEQYGIYINGDTVVRPHYYKNFHPKECIVGGGVVC 136
            ..:|| :||||::|.|||||.:   ::|..:.:|||.:|.|:|:|..:.|.|.|||.:|..||:.
 Worm    83 WKFVE-EGGSLMILSGEGGERQ---SLNEMIAKYGITVNKDSVIRTVFLKYFDPKEALVANGVIN 143

  Fly   137 ESMWRHLLKLDIEKVYYDFSDEKYKIHFQYPYGATLNV-SEPANVLLTTGPVVYPFNRPLVGYFT 200
                |.:.....:.|..:.......:.|.||||.||:| :..:||:|::|...:|.:||:..:..
 Worm   144 ----RAIAVAAKKNVSTEQKHNSQALSFIYPYGCTLDVNNRMSNVVLSSGSTSFPTSRPVAAFHE 204

  Fly   201 N-----GKGGKILAVGSGYIWHDKYLQDKTNDAMFEYLIK-LLGGDEITYSHLDFNDVELSDNKH 259
            .     .|.|::..|||..::||.|:..:.|..:|:..:: |:.|.|:  :.:|..:.|::|..:
 Worm   205 TKLNEMKKKGRVCVVGSVSMFHDTYIDKEENGKIFDTFVEFLVNGLEL--NTIDAAEPEINDYTN 267

  Fly   260 FTDIGFLADMPKACLID-SIGTDMPTDFKQMFDMRLCRLSNRLLKDVMDTYEQLHVKYEPLKIIK 323
            ..|...::...|.|:.: .:...:.:||.::.|..|...:.:.....:..||.|::...||.:::
 Worm   268 IPDHIHMSQQIKVCMYEGELDQAISSDFMKIMDTSLHSFNLKHWPMTIRLYEALNLSPPPLTLVE 332

  Fly   324 PQFEIPLPNVQLATFPPIFSEPSAPPLELYDLDETFSGARSQLAHMTGQVLQALQSKEPQRRALN 388
            ||||:|:|..|.|.|||.|.|...|||||:||||.||....||:.:      |.:|:|
 Worm   333 PQFELPMPPFQPAVFPPTFQELPMPPLELFDLDEQFSSPEIQLSQL------ANRSEE------- 384

  Fly   389 QRELENYIKECARITAIVDE--RQDMAAREILNIVARQIISYR 429
             .:|..:|::...||.|..|  |.:...::|:.:...:::.::
 Worm   385 -EDLIFFIEKAGEITGISAELTRSERTPKKIIELAVSKLMLFK 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IFT52	NP_609045.2	ABC_transp_aux	<1..115	CDD:420021	32/107 (30%)
osm-6	NP_741633.1	ABC_transp_aux	<50..122	CDD:304962	24/75 (32%)
		MDR	<202..>228	CDD:302572	6/25 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167212
Domainoid	1	1.000	185	1.000	Domainoid score	I2008
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9335
Inparanoid	1	1.050	186	1.000	Inparanoid score	I2605
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56686
OrthoDB	1	1.010	-	-		D284059at33208
OrthoFinder	1	1.000	-	-		FOG0008331
OrthoInspector	1	1.000	-	-		oto18682
orthoMCL	1	0.900	-	-		OOG6_104610
Panther	1	1.100	-	-	LDO	PTHR12969
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5524
SonicParanoid	1	1.000	-	-		X6312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940