DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31637 and Chst2

DIOPT Version :9

Sequence 1:	NP_001285677.1	Gene:	CG31637 / 33914	FlyBaseID:	FBgn0051637	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	XP_006243615.1	Gene:	Chst2 / 367145	RGDID:	1306988	Length:	530	Species:	Rattus norvegicus

Alignment Length:	506	Identity:	120/506 - (23%)
Similarity:	188/506 - (37%)	Gaps:	140/506 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 RMSRRANLIGICGVSSLCILLLIATTQHRPLTTPFNQ------------SAGRDQGASVDGGPSN 111
            ::.||..|:...|.:.|.:|.::....::....|..|            :||...|.  .|.|..
  Rat    49 KVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAVGAAGAGWGR--PGSPPA 111

  Fly   112 SLARSAFYDRFQQQLQQQQQSSQTAVYNLTATIVDVLSAQRSRILAEMENFEYPRGGAERLTDMT 176
            :..|:           ..:...:|......|.:..|.:|....:           |.|..|.:.|
  Rat   112 APPRA-----------HSRMDPRTPYRPPAAGVGAVPAAAAGSV-----------GAAASLGNAT 154

  Fly   177 PETNGTPVRSVVV---TSWRSGSTFLGDILNSIPGNFYHYEPLLDFGIKQIRDPDD----QELAV 234
            ..|.|...:..:|   |:|||||:|.|::.|..|..|:.|||:  :.:.|...|.|    |..|.
  Rat   155 RGTRGGGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPV--WHVWQKLYPGDAVSLQGAAR 217

  Fly   235 QNLKNLLNCDYADMIDYLNFGK-----THTYLFEHNTR------------------LWD--VCRE 274
            ..|..|..||.:....|...|.     |...:|...|.                  |.|  ||::
  Rat   218 DMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKK 282

  Fly   275 FPRFCWRPAFLTRF---CRLFPIQSMKTVRL-RLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQSR 335
            .|     |..|.||   ||.:....:|.||: .:|....||:|.:| .::::.||||||....||
  Rat   283 CP-----PQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLKDPAL-DLKVIHLVRDPRAVASSR 341

  Fly   336 ---RHRVWCGGNEDCE-----DPR----------------------------------LVCQDLR 358
               ||.:.   .|..:     |||                                  ::|..:.
  Rat   342 IRSRHGLI---RESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGMGGPADYHALGAMEVICNSMA 403

  Fly   359 DDYKTAEVLLLKYP----SRFRTVRYEDLSLSPSEMTQDILQFYGLPFDPAVEEFLDTHTKVNIG 419
            ...:||    |:.|    ..:..||||||...|.:..:.:..|.||...|.:|:|....|..:
  Rat   404 KTLQTA----LQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGS-- 462

  Fly   420 GVSS-----TYRDSRSAPFHWMQDLKPEEIKQIQDVCTEAMDLWGYRRIEN 465
            |.||     :.|::..|...|...|..::|||:::.|.:.|.:.||.|:.:
  Rat   463 GSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNS 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31637	NP_001285677.1	Sulfotransfer_1	187..459	CDD:304426	93/358 (26%)
Chst2	XP_006243615.1	Sulfotransfer_1	<311..507	CDD:304426	50/205 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338568
Domainoid	1	1.000	86	1.000	Domainoid score	I7883
eggNOG	1	0.900	-	-		E1_299AF
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I4931
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1246608at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9120
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10704
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X233
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.900