DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31637 and si:ch73-62b13.1

DIOPT Version :9

Sequence 1:	NP_001285677.1	Gene:	CG31637 / 33914	FlyBaseID:	FBgn0051637	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001076420.1	Gene:	si:ch73-62b13.1 / 100002270	ZFINID:	ZDB-GENE-050420-366	Length:	420	Species:	Danio rerio

Alignment Length:	400	Identity:	109/400 - (27%)
Similarity:	174/400 - (43%)	Gaps:	93/400 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 LSAQRSRILAEMENFEYP----------RGGAER---LTD---MTPETNGTPVRS--VVVTSWRS 194
            |..|.:.|.:..::|..|          :|..:|   |.|   :..||:|...|.  ::....||
Zfish    16 LGVQYTAIRSLHDSFSGPCQDSTHCQVHQGKEQRWKSLCDDSRVLAETSGAAARKHILLFAQTRS 80

  Fly   195 GSTFLGDILNSIPGNFYHYEPLLDFGIKQI---------RDPDDQEL--AVQN-LKNLLNCDYAD 247
            ||:|.|.:.|..||.||.:|||  :.::|.         |..|.:.|  |.:: |.||.|||::.
Zfish    81 GSSFTGQLFNQHPGIFYLFEPL--YHVQQAFTNSSSRLQRALDGRALLGAYRDLLLNLYNCDFSF 143

  Fly   248 MIDYLN-----------FGKTHTYLFEHNTRLWDVCRE--------FPRFCWRP--------AFL 285
            :..|:.           |.::.:    |...:..||.|        .|...|.|        ...
Zfish   144 LESYIRPEPQDHMTGAFFRRSSS----HALCMTPVCPEGSEEIQAGQPDETWCPKKCQALNLTIA 204

  Fly   286 TRFCRLFPIQSMKTVRL-RLAQAEKLLEDQSLSSVRIVLLVRDPRGTMQSR------RHRVWCGG 343
            ::.|:.....::||||: .:.....|.||..| .:||:.||||||..:.||      :.|.|...
Zfish   205 SQACQDRNHVAIKTVRIPEIGDLRTLSEDPRL-DLRIIHLVRDPRAILASRMTAFASKFRAWKIW 268

  Fly   344 NEDCEDPRLV--------CQDLRDDYKTAEVLLLKYPS----RFRTVRYEDLSLSPSEMTQDILQ 396
            |.....||.|        |:|:....:|.   ||| |:    |:..||||||:|:|.|..::|.:
Zfish   269 NATGRQPRYVDLTQITRTCKDIEYSVETG---LLK-PTWLRGRYLLVRYEDLALNPEEKAKEIYR 329

  Fly   397 FYGLPFDPAVEEFLDTHTKVNIGGVS------STYRDSRSAPFHWMQDLKPEEIKQIQDVCTEAM 455
            |.||.....|.:::..:|..::...|      ||.|||::....|...|..:.:|.:|.:|...:
Zfish   330 FLGLDLHQRVLKWIVDNTNSSVPSSSEWNYKYSTTRDSKATAQSWRVHLNFDIVKTVQSLCNRTL 394

  Fly   456 DLWGYRRIEN 465
            .|.||:.:::
Zfish   395 ALLGYKLVQS 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31637	NP_001285677.1	Sulfotransfer_1	187..459	CDD:304426	94/335 (28%)
si:ch73-62b13.1	NP_001076420.1	Sulfotransfer_1	<213..398	CDD:304426	59/189 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578076
Domainoid	1	1.000	89	1.000	Domainoid score	I7802
eggNOG	1	0.900	-	-		E1_299AF
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I5000
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1246608at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26208
orthoMCL	1	0.900	-	-		OOG6_102425
Panther	1	1.100	-	-	O	PTHR10704
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X233
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.760