Protein Alignment RAB43 and RabX6

DIOPT Version :10

• Sequence 1: NP_940892.1
• Gene: RAB43 / 339122
• HGNCID: 19983
• Length: 212
• Species: Homo sapiens
• Sequence 2: NP_001261219.1
• Gene: RabX6 / 38084
• FlyBaseID: FBgn0035155
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 69/209 - (33%)
• Similarity: 109/209 - (52%)
• Gaps: 21/209 - (10%)

Human    20 KLVLVGDASVGKTCVVQRFKTGAF---SERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQERFR 81
            |::|.||..|||:.:.:||.|..|   ::|: ||:|:|...:...:..|::|||:|||.|.||..
  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRK-STLGLDHIDREYSVNEKQIKLQLWDTGGMERVA 73

Human    82 TITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELR-EVSLAE 145
            ::|.|||:.|.||||.:.:...:||.|:...:.|:..|| .|....:.||||||.... |||..|
  Fly    74 SVTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYA-ENAKIFICGNKSDLDGREPEVSDEE 137

Human   146 AQSLAE--HYDILCAIETSAKDSSNVEEAFLRVATELIMRHGGPL----FSEKSPDHIQLNSKDI 204
            .::..|  |..|....:||.:..:.|||.|..::.:|:..:...:    ...||   .|:::...
  Fly   138 VEAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLVHANRSKMELQALEHKS---FQVDTASS 199

Human   205 G------EGWGCGC 212
            |      :...|||
  Fly   200 GAATNEEDASSCGC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB43	NP_940892.1	Rab19	16..180	CDD:133267	61/165 (37%)
		Effector region. /evidence=ECO:0000250	47..55		3/7 (43%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	61/163 (37%)