Protein Alignment RAB43 and Rab14

DIOPT Version :10

• Sequence 1: NP_940892.1
• Gene: RAB43 / 339122
• HGNCID: 19983
• Length: 212
• Species: Homo sapiens
• Sequence 2: NP_788056.1
• Gene: Rab14 / 34840
• FlyBaseID: FBgn0015791
• Length: 239
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 82/209 - (39%)
• Similarity: 118/209 - (56%)
• Gaps: 12/209 - (5%)

Human    15 YDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQER 79
            |:::||.:::||..|||:|::.:|....|......||||:|..:.:|:..|::||||||||||||
  Fly    32 YNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQER 96

Human    80 FRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELREVSLA 144
            ||.:|:||||.|.||::.||||:||::..:..|:.|.|.....:.|..||||||||...|||:..
  Fly    97 FRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDLESTREVTYE 161

Human   145 EAQSLAEHYDILCAIETSAKDSSNVEEAFLRVATELIMR-----------HGGPLFSEKSPDHIQ 198
            ||:..|:...:: .:|.||....|||||||..|.::...           ..|.......|....
  Fly   162 EAKEFADENGLM-FLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGVQHRPSQPSRTS 225

Human   199 LNSKDIGEGWGCGC 212
            |:|:..|....|.|
  Fly   226 LSSEATGAKDQCSC 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB43	NP_940892.1	Rab19	16..180	CDD:133267	74/163 (45%)
		Effector region. /evidence=ECO:0000250	47..55		4/7 (57%)
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	74/165 (45%)