Protein Alignment RAB43 and RabX2

DIOPT Version :10

• Sequence 1: NP_940892.1
• Gene: RAB43 / 339122
• HGNCID: 19983
• Length: 212
• Species: Homo sapiens
• Sequence 2: NP_572627.1
• Gene: RabX2 / 31971
• FlyBaseID: FBgn0030200
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 69/193 - (35%)
• Similarity: 116/193 - (60%)
• Gaps: 13/193 - (6%)

Human    15 YDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQER 79
            :|:|||::::||:.|||:|::.||....|:|:...|:|:|...:::|:..:.:.||:|||:|.:|
  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68

Human    80 FRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSELREVSLA 144
            |.::..|.||||:|.:|.||||...||.::..|::::|:.....:..||:|||||....|:||:.
  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133

Human   145 EAQSLAEHYDILCAIETSAKDSSNVEEAFLRVATELIMRHG-----GPLFSE-------KSPD 195
            :..:.| |...|...|.|||...||.:.|..:|.::..|:.     .|:.||       :|||
  Fly   134 QGFNYA-HRGALGFEEVSAKSGMNVYDIFSSLAMDIYHRYVLHNPISPMPSEQEEEDAAESPD 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB43	NP_940892.1	Rab19	16..180	CDD:133267	62/163 (38%)
		Effector region. /evidence=ECO:0000250	47..55		2/7 (29%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	59/157 (38%)