DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9547 and POX1

DIOPT Version :9

Sequence 1:	NP_609040.1	Gene:	CG9547 / 33911	FlyBaseID:	FBgn0031824	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_011310.1	Gene:	POX1 / 852667	SGDID:	S000003173	Length:	748	Species:	Saccharomyces cerevisiae

Alignment Length:	479	Identity:	99/479 - (20%)
Similarity:	164/479 - (34%)	Gaps:	156/479 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ESQLTEEEVA------------IRDAFRGY-CQAELQPR-----VKMANR-LETFDKK------I 77
            |.::|.:::|            :|..||.. ...|||..     ..:.|: |..|||:      |
Yeast    75 EREITAKKIARLASYMEHDIKTVRKHFRDTDLMKELQANDPDKASPLTNKDLFIFDKRLSLVANI 139

  Fly    78 MEEIGS-----LGVLGCTIKGYGCAGVSSVAYGLLTREVERVDSAYRSAVSVQSSLAMGAIYDFG 137
            ..::|:     ||:.|..|||.|                  .|...|..:..:.:..|..||
Yeast   140 DPQLGTRVGVHLGLFGNCIKGNG------------------TDEQIRYWLQERGATLMKGIY--- 183

  Fly   138 SEEQKQRYLPSMAEGKLIGAFGLTEPNHGSDPAGMETRAKYDSKSKTYI-----LNGSKTWI--- 194
                              |.|.:||..|||:.|.::|||.||.::.|::     |..:|.||
Yeast   184 ------------------GCFAMTELGHGSNVAQLQTRAVYDKQNDTFVIDTPDLTATKWWIGGA 230

  Fly   195 ----TSAPIADVIVVWAKCEDGKVRGFLVDRKISG-----KGLETPKIEGKFSLRASPTGMILMD 250
                |.|.:...::|..|  |..|:.|:|..:...     .|:....|..|........|.|...
Yeast   231 AHSATHAAVYARLIVEGK--DYGVKTFVVPLRDPSTFQLLAGVSIGDIGAKMGRDGIDNGWIQFR 293

  Fly   251 EVRVPEEQLL-------------------PNVAGFSGPFSCLNNARYGIAWGALGAAETCVEIAR 296
            .|.:|.|.:|                   |.:...|| :|.|.:.|..:...:.........||.
Yeast   294 NVVIPREFMLSRFTKVVRSPDGSVTVKTEPQLDQISG-YSALLSGRVNMVMDSFRFGSKFATIAV 357

  Fly   297 QYTLDRKQFG--RPLAANQLIQKKLAD--AITEIALGLQACLHVGRLKDQKLHTPDMI------- 350
            :|.:.|:||.  :.|:..|||...|..  .:.::.:.........:|.|....|.|.:
Yeast   358 RYAVGRQQFAPRKGLSETQLIDYPLHQYRVLPQLCVPYLVSPVAFKLMDNYYSTLDELYNASSSA 422

  Fly   351 -------------------SLLKRNNTGKSLDIARQMRDMLGANGIS---------DEYHVIRHV 387
                               :.||..||.....:..::|...|.:|.|         |::     |
Yeast   423 YKAALVTVSKKLKNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDW-----V 482

  Fly   388 INLESVNTYEGTHDIHALILGRAI 411
            :..    |:||.:::.:|...::|
Yeast   483 VQC----TWEGDNNVLSLTSAKSI 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9547	NP_609040.1	GCD	29..417	CDD:173840	99/479 (21%)
CG9547	NP_609040.1	CaiA	41..417	CDD:224871	98/476 (21%)
POX1	NP_011310.1	AXO	18..702	CDD:173839	99/479 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810