DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9547 and Gcdh

DIOPT Version :9

Sequence 1:	NP_609040.1	Gene:	CG9547 / 33911	FlyBaseID:	FBgn0031824	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001102366.1	Gene:	Gcdh / 364975	RGDID:	1308829	Length:	447	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	272/397 - (68%)
Similarity:	325/397 - (81%)	Gaps:	2/397 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SSKAAAPKFNWQDPLNLESQLTEEEVAIRDAFRGYCQAELQPRVKMANRLETFDKKIMEEIGSLG 85
            |.|::.|.|:|:|||.||.|||.:|..|||.||.|||..|..|:.:|||.|.|.:.|:.|:|.||
  Rat    49 SVKSSRPVFDWKDPLVLEEQLTADEKLIRDTFRNYCQERLMSRILLANRNEVFHRDIVYEMGELG 113

  Fly    86 VLGCTIKGYGCAGVSSVAYGLLTREVERVDSAYRSAVSVQSSLAMGAIYDFGSEEQKQRYLPSMA 150
            |||.|||||||||||||||||||||:|||||.|||.:||||||.|..||.:|||||:|:|||.:|
  Rat   114 VLGPTIKGYGCAGVSSVAYGLLTRELERVDSGYRSMMSVQSSLVMHPIYTYGSEEQRQKYLPRLA 178

  Fly   151 EGKLIGAFGLTEPNHGSDPAGMETRAKYDSKSKTYILNGSKTWITSAPIADVIVVWAKCEDGKVR 215
            :|:|:|.||||||||||||..|||||:::..:|:|.|:|:|||||::|:||:.||||:|||..:|
  Rat   179 KGELLGCFGLTEPNHGSDPGSMETRARHNPSNKSYTLSGTKTWITNSPVADLFVVWARCEDNCIR 243

  Fly   216 GFLVDRKISGKGLETPKIEGKFSLRASPTGMILMDEVRVPEEQLLPNVAGFSGPFSCLNNARYGI 280
            |||:::.:  :||..|:||||||||||.||||:||.|.||||.:||||:..:|||.|||.|||||
  Rat   244 GFLLEKGM--RGLSAPRIEGKFSLRASATGMIIMDSVEVPEENVLPNVSSLAGPFGCLNTARYGI 306

  Fly   281 AWGALGAAETCVEIARQYTLDRKQFGRPLAANQLIQKKLADAITEIALGLQACLHVGRLKDQKLH 345
            .||.|||||.|:..||||.|||.|||.|||.|||:||||||.:|||.|||.|||.:||||||...
  Rat   307 TWGVLGAAEFCLHTARQYALDRIQFGVPLARNQLVQKKLADMLTEITLGLHACLQLGRLKDQDKA 371

  Fly   346 TPDMISLLKRNNTGKSLDIARQMRDMLGANGISDEYHVIRHVINLESVNTYEGTHDIHALILGRA 410
            ||:|:|||||||.||:||||||.||:||.||||||||||||.:|||:||||||||||||||||||
  Rat   372 TPEMVSLLKRNNCGKALDIARQARDILGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRA 436

  Fly   411 ITGLAAF 417
            |||:.||
  Rat   437 ITGIQAF 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9547	NP_609040.1	GCD	29..417	CDD:173840	267/387 (69%)
CG9547	NP_609040.1	CaiA	41..417	CDD:224871	259/375 (69%)
Gcdh	NP_001102366.1	GCD	57..443	CDD:173840	267/387 (69%)
Gcdh	NP_001102366.1	CaiA	69..443	CDD:224871	259/375 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337292
Domainoid	1	1.000	225	1.000	Domainoid score	I2458
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H130
Inparanoid	1	1.050	563	1.000	Inparanoid score	I1044
OMA	1	1.010	-	-		QHG61728
OrthoDB	1	1.010	-	-		D275334at33208
OrthoFinder	1	1.000	-	-		FOG0005817
OrthoInspector	1	1.000	-	-		oto95825
orthoMCL	1	0.900	-	-		OOG6_101810
Panther	1	1.100	-	-	LDO	PTHR42807
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4208
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770