back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9547 and ACADL

DIOPT Version :9

Sequence 1:	NP_609040.1	Gene:	CG9547 / 33911	FlyBaseID:	FBgn0031824	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001599.1	Gene:	ACADL / 33	HGNCID:	88	Length:	430	Species:	Homo sapiens

Alignment Length:	433	Identity:	116/433 - (26%)
Similarity:	184/433 - (42%)	Gaps:	62/433 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PCAR--------RLASTSSKAAAPKFNWQDPLNLESQLTEEEVAIRDAFRGYCQAELQPRVKMAN 68
            |.||        ||.:.|:|...       .:.:....:.|....|.:.|.:.|.|:.|......
Human    23 PAARCSHSGGEERLETPSAKKLT-------DIGIRRIFSPEHDIFRKSVRKFFQEEVIPHHSEWE 80

  Fly    69 RLETFDKKIMEEIGSLGVLGCTIKGYGCAGVSSVAY-GLLTREVERVDSAYRSAVSVQSSLAMGA 132
            :.....:::.|:.|..|:||..|..: ..|:....| ..:..|.:...:......|:.|.:.|..
Human    81 KAGEVSREVWEKAGKQGLLGVNIAEH-LGGIGGDLYSAAIVWEEQAYSNCSGPGFSIHSGIVMSY 144

  Fly   133 IYDFGSEEQKQRYLPSMAEGKLIGAFGLTEPNHGSDPAGMETRAKYDSKSKTYILNGSKTWITSA 197
            |.:.|||||.:.::|.|..||.|||..:|||..|||..|::|.||.|...  :||||||.:|::.
Human   145 ITNHGSEEQIKHFIPQMTAGKCIGAIAMTEPGAGSDLQGIKTNAKKDGSD--WILNGSKVFISNG 207

  Fly   198 PIADVIVVWA----------------KCEDGKVRGFLVDRKISGKGLETPKIEGKFSLRASPTGM 246
            .::||::|.|                ..|:| ::||:..||:.           |..|:|..|..
Human   208 SLSDVVIVVAVTNHEAPSPAHGISLFLVENG-MKGFIKGRKLH-----------KMGLKAQDTAE 260

  Fly   247 ILMDEVRVPEEQLL-PNVAGFSGPFSCLNNARYGIAWGALGAAETCVEIARQYTLDRKQFGRPLA 310
            :..:::|:|...|| ....||......|...|..||..|:.|:|...|..|.|...||.||:.:|
Human   261 LFFEDIRLPASALLGEENKGFYYIMKELPQERLLIADVAISASEFMFEETRNYVKQRKAFGKTVA 325

  Fly   311 ANQLIQKKLADAITEIALG---LQACLHVGRLKDQKLHTPDM----ISLLKRNNTGKSLDIARQM 368
            ..|.:|.|||:..|.|.:.   :..||.:...|.....|..|    .|.|:.:       :|...
Human   326 HLQTVQHKLAELKTHICVTRAFVDNCLQLHEAKRLDSATACMAKYWASELQNS-------VAYDC 383

  Fly   369 RDMLGANGISDEYHVIRHVINLESVNTYEGTHDIHALILGRAI 411
            ..:.|..|...||.:.:..::......|.||::|...::.|.|
Human   384 VQLHGGWGYMWEYPIAKAYVDARVQPIYGGTNEIMKELIAREI 426

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.