Protein Alignment CG31638 and CGNL1

DIOPT Version :10

• Sequence 1: NP_723186.2
• Gene: CG31638 / 33910
• FlyBaseID: FBgn0051638
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_005254783.1
• Gene: CGNL1 / 84952
• HGNCID: 25931
• Length: 1303
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 121/552 - (21%)
• Similarity: 227/552 - (41%)
• Gaps: 127/552 - (23%)

  Fly     3 QTASTTQSVTAAPAGGSRRNEVGGVGVIGTTMSAR---------YGET-EWEARESQRQRELHEA 57
            :.|:....|.|:.:..|.:::.      ||.|..:         .|.: |.|.|.:|.||::.:.
Human   797 EEATKNVEVLASRSNTSEQDQA------GTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDL 855

  Fly    58 RARAAQMEKTMKWWSDCTANWREKWSKVRNERNKA---------------------REESKQLSL 101
            :...|:.::|:|.:........|.....|.|..:|                     .:|.||||.
Human   856 KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSE 920

  Fly   102 KLDGVMKEAHSLKREKNDLELQITQLKKEMEKVHTLMMKHAGQFHRADTSEDAEANGRDANCSPD 166
            ||....::...|:|.||::|.:...|.|.:||:         |...||..|.:    |.:.....
Human   921 KLKEESEQKEQLRRLKNEMENERWHLGKTIEKL---------QKEMADIVEAS----RTSTLELQ 972

  Fly   167 ISSDGLKNINSEDGLVTKLPNDVKDLDIEEFAMKGAMPKHLTELDEAAAAEEKRLIQQLSKD-DF 230
            ...|..|..|..:  :.::...:|:..:|      |....||.:   ...:|.||:::..:| ..
Human   973 NQLDEYKEKNRRE--LAEMQRQLKEKTLE------AEKSRLTAM---KMQDEMRLMEEELRDYQR 1026

  Fly   231 DEDYLLQKISMLQLRLDEAQKTLQAE---RDEKLELHKSIE----KLTLEIQDVRGRQEEMRSAK 288
            .:|..|.|..:|:..|.:.:..|:|:   :|::..|.|.:|    :|.:|:::.|
Human  1027 AQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEER---------- 1081

  Fly   289 QEAVRELLTLQEQHRAEMRIVNNSLQEEIAARENLERRLTELRTELEHLQAENASEWGKRERLES 353
                                 |||        :.|..|::..|.::|.|:.|...|...|:.||.
Human  1082 ---------------------NNS--------DLLSERISRSREQMEQLRNELLQERAARQDLEC 1117

  Fly   354 EKLAMERDNKKLRAEL----RDYQERSDRKCRPMQANDVEL--RALQQELSERNKEISEVKMSHA 412
            :|:::||.||.|::.:    ..|:...:.....|:|...||  |...:|....|.::|..::..
Human  1118 DKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLER- 1181

  Fly   413 KLKKLLAETNTELGHAVRRAEQYEAEVKRLRQRVEELKRELAGAEDELDSAVNQVRRLQRSNDEL 477
            |:|:|:.:.:.|......:.:|....:|.::::|||       ||:|:|...:..::|||..:|.
Human  1182 KVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEE-------AEEEIDRLESSKKKLQRELEEQ 1239

  Fly   478 VGQTEGLQVQIQHLQN-----RRAPSPQLRGM 504
            :...|.||.|:..::.     ::.||..|..|
Human  1240 MDMNEHLQGQLNSMKKDLSRLKKLPSKVLDDM 1271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31638	NP_723186.2	Smc	<233..>496	CDD:440809	63/280 (23%)
CGNL1	XP_005254783.1	Myosin_tail_1	<615..1257	CDD:460256	117/536 (22%)