Protein Alignment CG31638 and myh11b

DIOPT Version :10

• Sequence 1: NP_723186.2
• Gene: CG31638 / 33910
• FlyBaseID: FBgn0051638
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_017210292.1
• Gene: myh11b / 566080
• ZFINID: ZDB-GENE-101124-2
• Length: 2005
• Species: Danio rerio
• Alignment Length: 635
• Identity: 128/635 - (20%)
• Similarity: 268/635 - (42%)
• Gaps: 136/635 - (21%)

  Fly    44 EARESQRQRELHEARARAAQMEKTMKWWSDCTANWREKWSKVRN-ERNKAREES--KQLSLKLDG 105
            |.::::.|:|..:...|.|          |.::|..|:..|.:| .:.||:.||  ..|.:::..
Zfish  1008 EDQKNKLQKEKQQLEERLA----------DFSSNLAEEEEKSKNLTKLKAKHESMISDLEVRMKK 1062

  Fly   106 VMKEAHSLKREKNDLELQITQLKKEMEKVHTLMMKHAGQFHRAD-------TSEDAEANGRDANC 163
            ..|....:::.|..||.:.:.|:::|:.:.||:.:...|..|::       .|.:||:..:
Zfish  1063 EEKSRQDVEKAKRKLETEHSDLQEQMKNLQTLIAELKTQQARSEMEIQELQASVEAESTQK---- 1123

  Fly   164 SPDISSDGLKNINSEDGLVTKLPNDV--------------KDLDIEEFAMKGAMPKHLTELDEAA 214
                 |:.||.|:..:||:::|.:::              |:|:.|..|::..:.   ..||..|
Zfish  1124 -----SNALKKIHEMEGLLSELQDELEAEQGAGRKSEKARKELEEELSALRTELE---DSLDTTA 1180

  Fly   215 AAEEKRLIQQLSKDDFDEDYLLQKISMLQLRLDEAQKTLQAERDEKLELH-KSIEKLTLEIQDVR 278
            ..:|.|..::            |:::||:..:::..::.:|:..|..:.| :::::|:.::...:
Zfish  1181 VQQELRAKRE------------QEVAMLKKLIEDEGRSHEAQVHELKQKHAQAVDELSQQLDQSK 1233

  Fly   279 GRQEEMRSAKQEAVRELLTLQEQHRAEMRIVNNSLQEEIAARENLERRLTELRTELEHLQAE-NA 342
            ..:..:..|||...:|:..|           |.:|:....|:::||::..::.|:|..||.. |.
Zfish  1234 RAKATLEKAKQALEKEVGDL-----------NGNLRSLGNAKQDLEQKKKKVETQLADLQTRFNE 1287

  Fly   343 SEWGKRERL---------------------ESEKLAMERDNKKLRAELRDYQERSDRKCRPMQAN 386
            || .|||.|                     ||:.:.:.:|...|.::|:|.||....:.|.....
Zfish  1288 SE-RKREELGDAVSKLNTEYNNVNSILNEAESKNIKLSKDVVSLNSQLQDAQELLAEETRQKLNF 1351

  Fly   387 DVELRALQQELSERNKEISEVKMSHAKLKKLLAETNTELGHAVRRAEQYEAEVKRLRQRVEELKR 451
            ...||.::.|.:...::|.|...:...:::.::..||:|..|.:|.::|.:..:.|.:..:.|:|
Zfish  1352 STRLRQMEDERNGLLEQIDEETEARRNVERHVSSLNTQLSEAKKRLDEYSSNFQMLEESKKRLQR 1416

  Fly   452 ELAGAEDEL-------DSAVNQVRRLQRSNDELVGQTEGLQVQIQHLQNRRAPSPQL-------- 501
            :|...:.||       |.:......||:..|:::...:..:..:.:::.::....|:
Zfish  1417 DLEATKGELEEKTASYDKSEKTKNHLQQELDDVLLDLDNQRQLVSNMEKKQRKFDQMLADEKTLS 1481

  Fly   502 ------RGMGGVQLRNK--------IAVELPNDCLPNINDLRQIFDDSQAGLRSSHNGSDAAMHH 552
                  |.....:.|.|        .|:|.....|..:..|.:........|.||.:..:|  |.
Zfish  1482 SKYSQERDCAEAEAREKETKCLALTRALEECQGSLRELEKLNKTLRTDMEDLISSKDNKNA--HE 1544

  Fly   553 AASVKRS--SHTERTLLQQQQSSAAASAAAAAAAAAAFFDAKPTHLEENI 600
            ....||:  :..|...:|.::......||.         ||| .|||.|:
Zfish  1545 LEKTKRALEAQVEEMTIQMEELEDELQAAE---------DAK-LHLEVNM 1584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31638	NP_723186.2	Smc	<233..>496	CDD:440809	58/292 (20%)
myh11b	XP_017210292.1	Myosin_N	32..74	CDD:460670
		MYSc_class_II	97..788	CDD:276951
		Myosin_tail_1	865..1943	CDD:460256	128/635 (20%)