DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31638 and Ccdc102a

DIOPT Version :9

Sequence 1:	NP_723186.2	Gene:	CG31638 / 33910	FlyBaseID:	FBgn0051638	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_001028705.2	Gene:	Ccdc102a / 234582	MGIID:	2686927	Length:	549	Species:	Mus musculus

Alignment Length:	487	Identity:	208/487 - (42%)
Similarity:	292/487 - (59%)	Gaps:	62/487 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TMSARYGETEWEARESQRQRELHEARARAAQMEKTMKWWSDCTANWREKWSKVRNERNKAREESK 97
            |..|...:.:||:||..|.|||.||||||.||||||:|||||||||||||||||.|||:||||.:
Mouse    58 TAPALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVR 122

  Fly    98 QLSLKLDGVMKEAHSLKREKNDLELQITQLKKEMEKVHTLMMKHAGQFHRADTSEDAEANGRDAN 162
            ||..:||.:.||....:||:.:.:.:.....:|:.::.       |....||.:.|..
Mouse   123 QLRQRLDTLTKELAGARRERQEAQGECEARGRELARLR-------GVHSAADKTHDGP------- 173

  Fly   163 CSPDISSDGLKNINSEDGLVTKLPNDVKDLDIEEFAMK------------------------GAM 203
             .|:...:.:::|.:|      .|...::||:.|..:|                        |..
Mouse   174 -EPEREQEPVRDIGAE------RPPGSQELDLVESLLKSRPEEPEGCWDACSVAAGGPRVSSGRQ 231

  Fly   204 PKHLTELDEAAAAEEKRLIQQLSKDDFDEDYLLQKISMLQLRLDEAQKTLQAERDEKLELHKSIE 268
            .::....::.|:.||.                ..|::.|:|||||:||.|..||::||.|.|:||
Mouse   232 DRNRLPWEDTASTEED----------------ASKLTALRLRLDESQKVLLKEREDKLALSKNIE 280

  Fly   269 KLTLEIQDVRGRQEEMRSAKQEAVRELLTLQEQHRAEMRIVNNSLQEEIAARENLERRLTELRTE 333
            ||..|:...:.:.||:...|||.:::|..|:|.|:.|:..::..|::|:.||.:::|::.|||.|
Mouse   281 KLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGE 345

  Fly   334 LEHLQAENASEWGKRERLESEKLAMERDNKKLRAELRDYQERSDRKCRP-MQANDVELRALQQEL 397
            :|.||||||:|||:|||||:|||.:||:||||||::.|.:|...|:.|. ..|.|.:|||.|..|
Mouse   346 MERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAAL 410

  Fly   398 SERNKEISEVKMSHAKLKKLLAETNTELGHAVRRAEQYEAEVKRLRQRVEELKRELAGAEDELDS 462
            .|:|||::::|..|.||||...|...||.||.||.||:|.|||:||.||||||:|||.||||||.
Mouse   411 FEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDE 475

  Fly   463 AVNQVRRLQRSNDELVGQTEGLQVQIQHLQNR 494
            |.||.|:||||.||...|:|.||||::|||:|
Mouse   476 AHNQARKLQRSLDEQTEQSENLQVQLEHLQSR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31638	NP_723186.2	DUF4201	284..457	CDD:290581	88/173 (51%)
		Ax_dynein_light	<300..369	CDD:287215	38/68 (56%)
		RILP-like	<312..448	CDD:304877	73/136 (54%)
Ccdc102a	NP_001028705.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..61		1/2 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..195		11/80 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..248		4/56 (7%)
		Smc	<242..>516	CDD:224117	140/282 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	472..496		14/23 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	509..549
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	205	1.000	Domainoid score	I2931
eggNOG	1	0.900	-	-		E1_28K4K
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13240
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2191
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005832
OrthoInspector	1	1.000	-	-		oto92701
orthoMCL	1	0.900	-	-		OOG6_108934
Panther	1	1.100	-	-	LDO	PTHR46292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3433
SonicParanoid	1	1.000	-	-		X5576
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.850