DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31638 and F53F10.1

DIOPT Version :9

Sequence 1:	NP_723186.2	Gene:	CG31638 / 33910	FlyBaseID:	FBgn0051638	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_491236.1	Gene:	F53F10.1 / 171959	WormBaseID:	WBGene00018763	Length:	241	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	78/275 - (28%)
Similarity:	124/275 - (45%)	Gaps:	73/275 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 RYGETEWEARESQRQRELHEARARAAQMEKTMKWWSDCTANWREKWSKVRNERNKAREESKQLSL 101
            |...|:|:..|..|..||.|||.|||||||||:|||.|||:||.:||.||:|||:||||::.|.|
Worm    30 RCQHTDWDICERIRLGELKEARDRAAQMEKTMRWWSSCTADWRNRWSAVRDERNRAREEAETLRL 94

  Fly   102 KLDGVMKEAHSLKREKNDLELQITQLKKEMEKVHTLMMKHAGQFHRADTSEDAEANGRDANCSPD 166
            ..|.:::|...|                            |.|.:..|:..|...  .:.:..|:
Worm    95 NYDLLLEEKRFL----------------------------AEQLYHVDSESDEPK--LEISQKPE 129

  Fly   167 ISSDGLKNINSEDGLVTKLPNDVKDLDIEEFAMKGAMPKHLTELDEAAAAEEKRLIQQLSKDDFD 231
            |  ||.|. |:....:..:..|...:.::.:                :||:.:.::::.|.|:
Worm   130 I--DGTKR-NAVVQTIHSISCDPPSILVKSY----------------SAAQIEAVLREPSVDE-- 173

  Fly   232 EDYLLQKISMLQLRLDEAQKTLQAE----RDEKLELHKSIEKLTLE---IQDVRGRQEEMRSAKQ 289
                    ..::....:..:.|:||    :|:..||:|..||:..:   |||:|.|.:.|.
Worm   174 --------PPVETTKSDINEELKAENEFLKDQANELNKCREKIETDGKTIQDLRLRIQSME---- 226

  Fly   290 EAVRELLTLQEQHRA 304
               |||:..:...||
Worm   227 ---RELMAAKNSKRA 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31638	NP_723186.2	DUF4201	284..457	CDD:290581	6/21 (29%)
		Ax_dynein_light	<300..369	CDD:287215	2/5 (40%)
		RILP-like	<312..448	CDD:304877
F53F10.1	NP_491236.1	SMC_prok_A	<46..>241	CDD:274009	73/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28K4K
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005832
OrthoInspector	1	1.000	-	-		oto18454
orthoMCL	1	0.900	-	-		OOG6_108934
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3433
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830