Protein Alignment epsilonCOP and Cope

DIOPT Version :10

• Sequence 1: NP_609037.1
• Gene: epsilonCOP / 33908
• FlyBaseID: FBgn0027496
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_067513.1
• Gene: Cope / 59042
• MGIID: 1891702
• Length: 308
• Species: Mus musculus
• Alignment Length: 289
• Identity: 112/289 - (38%)
• Similarity: 169/289 - (58%)
• Gaps: 10/289 - (3%)

  Fly    14 LFDARNEYYIGNFMGSIN------FVLPEQGTAGPELLSYMYLSYLAIDSGRIVASDIKEGNSTP 72
            |||.:|.:|||::...||      ...||:..   |...::|.:|||.....:|..:||..::..
Mouse    19 LFDVKNAFYIGSYQQCINEAQRVKLSSPEREV---ERDVFLYRAYLAQRKYGVVLDEIKPSSAPE 80

  Fly    73 LQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETN-IWHLATAIVYCHDGQFENALKILHGSTN 136
            |||:|:..|.....::.:.::.:|..:::...|.|| .:.|..|.:|.||...:.||:.||....
Mouse    81 LQAVRMFAEYLASENQRDSIVLELDREMSRSVDVTNTTFLLMAASIYFHDQNPDAALRTLHQGDG 145

  Fly   137 LESMALSVQCLLRLQRVDLAKQLVAKMQEISDDATLTQLAQAWVALAQGTEQMQDAFHIYQEFCE 201
            ||.||:::|.||:|.|:|||::.:.|||:..:||||||||.|||.||.|.|::|:|::|:||..:
Mouse   146 LECMAMTIQILLKLDRLDLARKELKKMQDQDEDATLTQLATAWVNLAVGGEKLQEAYYIFQELAD 210

  Fly   202 KFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAHLTGKPTEAITRNLE 266
            |..||..||||||..|....|:|.|:.||:|:|.|.....:|||||:|.:...|||.|...|.|.
Mouse   211 KCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDSGHPETLINLIVLSQHLGKPPEVTNRYLS 275

  Fly   267 QLRQFYPKSDFVTDLDKKSAEFDRLCLQY 295
            ||:..:....|:.:...|..:||||.:||
Mouse   276 QLKDAHRAHPFIKEYQAKENDFDRLAMQY 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonCOP	NP_609037.1	Coatomer_E	12..296	CDD:398419	112/289 (39%)
		TPR repeat	175..201	CDD:276809	14/25 (56%)
		TPR repeat	206..236	CDD:276809	15/29 (52%)
Cope	NP_067513.1	Coatomer_E	17..305	CDD:398419	112/289 (39%)
		TPR repeat	185..210	CDD:276809	13/24 (54%)
		TPR repeat	215..245	CDD:276809	15/29 (52%)