Protein Alignment epsilonCOP and cope

DIOPT Version :10

• Sequence 1: NP_609037.1
• Gene: epsilonCOP / 33908
• FlyBaseID: FBgn0027496
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001007365.1
• Gene: cope / 492492
• ZFINID: ZDB-GENE-041114-59
• Length: 300
• Species: Danio rerio
• Alignment Length: 300
• Identity: 122/300 - (40%)
• Similarity: 181/300 - (60%)
• Gaps: 9/300 - (3%)

  Fly     1 MSRQQNEEDTNSVLFDARNEYYIGNFMGSINFVLPEQGTAGPELLS----YMYLSYLAIDSGRIV 61
            |:.||:|.|.   |||.:|.:|||::...|| ...:..|:|||..|    ::|.:|:|.....:|
Zfish     1 MASQQSEVDE---LFDVKNAFYIGSYQHCIN-EAQKVKTSGPEKESEKNIFLYRAYIAQRKYGVV 61

  Fly    62 ASDIKEGNSTPLQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETN-IWHLATAIVYCHDGQFE 125
            ..|||..::..|||:|:..|......:.:.::..|..|::...|.:| .:.|..|.:|.|:...:
Zfish    62 LDDIKPSSTEELQAVRMFAEYLSSEGKRDAIVADLDKKISKSVDVSNTTFLLMAASIYLHEMNTD 126

  Fly   126 NALKILHGSTNLESMALSVQCLLRLQRVDLAKQLVAKMQEISDDATLTQLAQAWVALAQGTEQMQ 190
            .||:.||...:||.||::||.||:|.|||:|::.:.|||:..:||||||||.|||.||.|.|::|
Zfish   127 AALRTLHQGESLECMAMTVQILLKLDRVDMARKELKKMQDQDEDATLTQLATAWVNLAIGGEKLQ 191

  Fly   191 DAFHIYQEFCEKFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAHLTG 255
            |||:|:||..:|:.||..||||||..|:...:::||:|||:::|.|.....:|||||:|.....|
Zfish   192 DAFYIFQEMSDKYSPTLLLLNGQAASHMAQNKWDEAESVLQDALDKDSGHPETLINLIVLTQHMG 256

  Fly   256 KPTEAITRNLEQLRQFYPKSDFVTDLDKKSAEFDRLCLQY 295
            ||.|...|.|.||:..:....|:.|...|..|||||.:||
Zfish   257 KPFEVTNRYLSQLKDAHKSHPFIKDYLAKKNEFDRLVMQY 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonCOP	NP_609037.1	Coatomer_E	12..296	CDD:398419	116/288 (40%)
		TPR repeat	175..201	CDD:276809	16/25 (64%)
		TPR repeat	206..236	CDD:276809	14/29 (48%)
cope	NP_001007365.1	Coatomer_E	9..297	CDD:398419	117/291 (40%)
		TPR repeat	177..202	CDD:276809	15/24 (63%)
		TPR repeat	207..237	CDD:276809	14/29 (48%)