Protein Alignment epsilonCOP and cope-1

DIOPT Version :10

• Sequence 1: NP_609037.1
• Gene: epsilonCOP / 33908
• FlyBaseID: FBgn0027496
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_499771.1
• Gene: cope-1 / 176766
• WormBaseID: WBGene00009732
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 282
• Identity: 84/282 - (29%)
• Similarity: 141/282 - (50%)
• Gaps: 4/282 - (1%)

  Fly    14 LFDARNEYYIGNFMGSINFVLPEQGTAGPELLS---YMYLSYLAIDSGRIVASDIKEG-NSTPLQ 74
            ||..||.:::|::...|...|........|...   |:|.||:|.....|...:|... .|..|.
 Worm     5 LFSIRNYFFLGSYQSCIGEALKFSSKNEEEKQEKDVYLYRSYIAQGQAFIPLKEIPAATKSADLA 69

  Fly    75 ALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETNIWHLATAIVYCHDGQFENALKILHGSTNLES 139
            |:|...|....|:..:::|.::.::||....::.|..:..|.:.......::|.:.:.....||:
 Worm    70 AVRRYAEFRNNPAAKKKILAEVQEEVASRNIKSEIAAVLAATILNEADLSQDAFRAVSRFEGLEA 134

  Fly   140 MALSVQCLLRLQRVDLAKQLVAKMQEISDDATLTQLAQAWVALAQGTEQMQDAFHIYQEFCEKFK 204
            .|..|..|:::.:..||...|.||.:|.:||||:|||.|.|.....:.:::||.:||.|..:|:.
 Worm   135 RASKVFILIKMNKRKLAIGEVKKMNQIDEDATLSQLANALVTSFGASGKVKDALYIYSEMSDKYG 199

  Fly   205 PTPALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAHLTGKPTEAITRNLEQLR 269
            .|..|...||||.:..:.|..|:.:|..:|.:.:.|.|.|||.:|.|.|..|..:.:.|.:.||:
 Worm   200 RTTDLEMHQAVVSILTQDYAAAEELLESALERDNKDADVLINSIVSAQLNEKDDDVVERFISQLK 264

  Fly   270 QFYPKSDFVTDLDKKSAEFDRL 291
            ..:|...:|.|.::|.|||||:
 Worm   265 HEHPNHPWVIDFNEKEAEFDRV 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonCOP	NP_609037.1	Coatomer_E	12..296	CDD:398419	84/282 (30%)
		TPR repeat	175..201	CDD:276809	9/25 (36%)
		TPR repeat	206..236	CDD:276809	10/29 (34%)
cope-1	NP_499771.1	Coatomer_E	3..291	CDD:398419	84/282 (30%)