Protein Alignment epsilonCOP and cope

DIOPT Version :10

• Sequence 1: NP_609037.1
• Gene: epsilonCOP / 33908
• FlyBaseID: FBgn0027496
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001106450.1
• Gene: cope / 100127627
• XenbaseID: XB-GENE-1008748
• Length: 299
• Species: Xenopus tropicalis
• Alignment Length: 295
• Identity: 116/295 - (39%)
• Similarity: 171/295 - (57%)
• Gaps: 7/295 - (2%)

  Fly     5 QNEEDTNSVLFDARNEYYIGNFMGSIN---FVLPEQGTAGPELLSYMYLSYLAIDSGRIVASDIK 66
            |.|.|.   |||.:|.:|||::...||   .|.|.......|...:::.:|:|.....:|..:|:
 Frog     4 QGEVDE---LFDVKNSFYIGSYQQCINEAQRVKPSSPEKEVERDVFLFRAYIAQRKYGVVLDEIR 65

  Fly    67 EGNSTPLQALRLVHEAFEQPSRTEELLEKLTDKVAGEEDETN-IWHLATAIVYCHDGQFENALKI 130
            ...:..|||:|:..|.....||.:.::..|..|:|...|.|| .:.|..|.:|.|||..:.||:.
 Frog    66 PNTNPELQAVRMFAEYLSNESRRDAIVSDLDKKMAKSVDITNSTFLLMAASIYFHDGNTDAALRA 130

  Fly   131 LHGSTNLESMALSVQCLLRLQRVDLAKQLVAKMQEISDDATLTQLAQAWVALAQGTEQMQDAFHI 195
            ||...:||.||..:|.||:|.|:|||::.:.||.|:.:||||||||.|||.:|.|.:::||||:|
 Frog   131 LHQGDSLECMATIIQVLLKLDRLDLARKELKKMVEVDEDATLTQLATAWVNIAVGGDKLQDAFYI 195

  Fly   196 YQEFCEKFKPTPALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAHLTGKPTEA 260
            :||..:|:..|..||||||..::|..::|:|:.||:|:|.|..:..:||||.:|.....|||.|.
 Frog   196 FQEMSDKYSSTLLLLNGQATCYMGQGKWEDAEGVLQEALDKDSSHPETLINFIVLTQHLGKPPEV 260

  Fly   261 ITRNLEQLRQFYPKSDFVTDLDKKSAEFDRLCLQY 295
            ..|.|.||:..:....|:.:...|..|||||.|||
 Frog   261 TNRYLSQLKDGHKNHPFIKEYQAKENEFDRLVLQY 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
epsilonCOP	NP_609037.1	Coatomer_E	12..296	CDD:398419	113/288 (39%)
		TPR repeat	175..201	CDD:276809	14/25 (56%)
		TPR repeat	206..236	CDD:276809	14/29 (48%)
cope	NP_001106450.1	Coatomer_E	8..296	CDD:398419	114/291 (39%)
		TPR repeat	138..165	CDD:276809	13/26 (50%)
		TPR repeat	170..202	CDD:276809	19/31 (61%)
		TPR repeat	207..235	CDD:276809	12/27 (44%)