DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KFase and Afmid

DIOPT Version :9

Sequence 1:	NP_001285676.1	Gene:	KFase / 33907	FlyBaseID:	FBgn0031821	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_017453019.1	Gene:	Afmid / 688283	RGDID:	1591143	Length:	312	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	72/278 - (25%)
Similarity:	129/278 - (46%)	Gaps:	61/278 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KDLDRDYFPSYHTTRFQDQPEPNLAVLEHFVRVTKQHGRELTEKQGIT----VDHLRYGEG-RQL 66
            ::|::.|.|.....|.:.:     .|:.:|:::    |.:.|:|...|    :| :.||:| .:.
  Rat    20 EELEKQYSPRRWVIRMKTE-----EVVGNFMQI----GSQATQKARATRRNQLD-VSYGDGVGEK 74

  Fly    67 VDVFYSEKTTNQAPLFVFVHGGYWQEMDMSMSCSIVGPLVRRGYRVAVMDYNLCPQVTLEQLMTQ 131
            :|:::.::.:...|||:|:||||||......|..:|.||..:|..|||:.|::.|:.||:|::.|
  Rat    75 MDIYFPDEDSKAFPLFMFLHGGYWQSGSKDDSAFMVNPLTAQGIVVAVVAYDIAPKGTLDQMVDQ 139

  Fly   132 FTHFLNWIFDYTEMTKVSSLTFAGHSAGAHLLAQILM--------RPNVITAQRSKMVWALIFLC 188
            .:..:  :|..........:...||||||||.|.:|:        .||         :..|:.:.
  Rat   140 VSRSV--VFLQRRYPSNEGIYLCGHSAGAHLAAMMLLASWTKHGVTPN---------IQGLLLVS 193

  Fly   189 GVYDLR-------------ELSNLESVNPKNILGLNERNIESVSPMLWEYTDVTVWNSTKIYVVA 240
            |:|||.             .|.:.|..:|:.:|     .:....|::..|         .:.|..
  Rat   194 GIYDLEPLVFTSQNDLLHMTLEDAERNSPQRLL-----EVAPARPVVPAY---------PVLVFV 244

  Fly   241 AEHDSTTFIEQSRHYADV 258
            |:|||..|..||:.:.:|
  Rat   245 AQHDSPEFHRQSKEFCEV 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KFase	NP_001285676.1	Aes	<67..297	CDD:223730	58/213 (27%)
KFase	NP_001285676.1	Abhydrolase	82..276	CDD:304388	55/198 (28%)
Afmid	XP_017453019.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339574
Domainoid	1	1.000	92	1.000	Domainoid score	I7464
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41731
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4657
OMA	1	1.010	-	-		QHG63382
OrthoDB	1	1.010	-	-		D608656at33208
OrthoFinder	1	1.000	-	-		FOG0002751
OrthoInspector	1	1.000	-	-		oto97518
orthoMCL	1	0.900	-	-		OOG6_107374
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4210
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.710