DRSC/TRiP Functional Genomics Resources

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Protein Alignment KFase and Aadac

DIOPT Version :10

Sequence 1:NP_609036.1 Gene:KFase / 33907 FlyBaseID:FBgn0287695 Length:300 Species:Drosophila melanogaster
Sequence 2:NP_075872.1 Gene:Aadac / 67758 MGIID:1915008 Length:398 Species:Mus musculus


Alignment Length:125 Identity:29/125 - (23%)
Similarity:44/125 - (35%) Gaps:36/125 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 FVHGGYWQEMDMSMSCSIVGPLVRRGYR-------------VAVMDYNLCPQVTLEQLMTQFTHF 135
            ::|||.|        |  :|......|.             |...||.|.|:....:........
Mouse   108 YIHGGGW--------C--LGSAAHFSYDTLSRWTAHKLDAVVVSTDYGLAPKHHFPRQFEDVYRS 162

  Fly   136 LNWIFDYTEMTKVS----SLTFAGHSAGAHLLA----QILMRPNVITAQRSKM-VWALIF 186
            |.|......:.|..    .:..:|.|||.:|.|    |::..|:|    :.|: |.|||:
Mouse   163 LRWFLQEDVLEKYGVDPRRVGVSGDSAGGNLAAAVTQQLIQDPDV----KIKLKVQALIY 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KFaseNP_609036.1 Aes 68..295 CDD:440422 29/125 (23%)
AadacNP_075872.1 Abhydrolase_3 106..356 CDD:400284 29/125 (23%)
Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3 110..112 1/1 (100%)

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