Protein Alignment KFase and NCEH1

DIOPT Version :10

• Sequence 1: NP_609036.1
• Gene: KFase / 33907
• FlyBaseID: FBgn0287695
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001139748.2
• Gene: NCEH1 / 57552
• HGNCID: 29260
• Length: 416
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 48/234 - (20%)
• Similarity: 80/234 - (34%)
• Gaps: 80/234 - (34%)

  Fly    83 VFVHGGYWQEMDMSMSCSIVGPLVRRGYR-------------VAVMDYNLCPQVTLEQLMTQFTH 134
            |::|||.|.....|.|.|....:  |.|.             :..::|.|.|:|          :
Human   110 VYIHGGGWALASASASWSPSDEI--RYYDELCTAMAEELNAVIVSIEYRLVPKV----------Y 162

  Fly   135 FLNWIFDYTEMTKV--------------SSLTFAGHSAGAHLLAQILMRPNVITAQRSKM-VWAL 184
            |...|.|....||.              ..:..:|.|||.:|.|.:..:.....:.::|: :.||
Human   163 FPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQAL 227

  Fly   185 IF-LCGVYDLRELSNLESVNPKNILGLNERNIESVSPMLWEYTDVTVW----------------- 231
            |: :....|....|..::||               :|:|..|..|..|
Human   228 IYPVLQALDFNTPSYQQNVN---------------TPILPRYVMVKYWVDYFKGNYDFVQAMIVN 277

  Fly   232 NSTKIYV-----VAAEHDSTTFIEQS--RHYADVLRKKG 263
            |.|.:.|     |.|..:.|:.:..|  ::|..|::..|
Human   278 NHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTG 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KFase	NP_609036.1	Aes	68..295	CDD:440422	48/234 (21%)
NCEH1	NP_001139748.2	Abhydrolase_3	109..389	CDD:400284	48/234 (21%)