Protein Alignment KFase and AFMID

DIOPT Version :10

• Sequence 1: NP_609036.1
• Gene: KFase / 33907
• FlyBaseID: FBgn0287695
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001138998.1
• Gene: AFMID / 125061
• HGNCID: 20910
• Length: 308
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 82/306 - (26%)
• Similarity: 136/306 - (44%)
• Gaps: 42/306 - (13%)

  Fly     7 KDLDRDYFPSYHTTRFQDQPEPNLAVLEHFVRVTKQHGRELTEKQGIT---VDHLRYGEGR-QLV 67
            ::|:..|.||....|..         .|..:|...|.|.|.|.:...|   :.|:.||:|. :.|
Human    21 EELENQYCPSRWVVRLG---------AEEALRTYSQIGIEATTRARATRKSLLHVPYGDGEGEKV 76

  Fly    68 DVFYSEKTTNQAPLFVFVHGGYWQEMDMSMSCSIVGPLVRRGYRVAVMDYNLCPQVTLEQLMTQF 132
            |:::.::::...|.|:|.||||||......|..:|.||..:|..|.::.|.:.|:.||:.::.|.
Human    77 DIYFPDESSEALPFFLFFHGGYWQSGSKDESAFMVHPLTAQGVAVVIVAYGIAPKGTLDHMVDQV 141

  Fly   133 THFLNWIFDYTEMTKVSSLTFAGHSAGAHLLAQILM--------RPNVITAQRSKMVWALIFLCG 189
            |..:.::.......|  .:...||||||||.|.:|:        .||         :.....:.|
Human   142 TRSVAFVQKRYPSNK--GIYLCGHSAGAHLAAMMLLADWTKHGVTPN---------LRGFFLVSG 195

  Fly   190 VYDLRELSNLESVNPKNI-LGLNERNIESVSPMLWEYTDVTVWNSTKIYVVAAEHDSTTFIEQSR 253
            |:||..:    ....:|: |.|...:.:..||.|.......|..:.::.||..:.||..|..||.
Human   196 VFDLEPI----VYTSQNVALQLTLEDAQRNSPQLKVAQAQPVDPTCRVLVVVGQFDSPEFHRQSW 256

  Fly   254 HYADVLR-----KKGYKASFTLFKGYDHFDIIEETAIDDSDVSRFL 294
            .:..||.     :..:||||......|||:|:|.....|:.:::.:
Human   257 EFYQVLPVQTLCQGEWKASFEELHDVDHFEIVENLTQKDNVLTQII 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KFase	NP_609036.1	Aes	68..295	CDD:440422	65/241 (27%)
AFMID	NP_001138998.1	Aes	77..>262	CDD:440422	53/199 (27%)
		HGGXW	95..99		3/3 (100%)