Protein Alignment Sec61alpha and Sec61a1

DIOPT Version :9

• Sequence 1: NP_001285674.1
• Gene: Sec61alpha / 33905
• FlyBaseID: FBgn0086357
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_954865.1
• Gene: Sec61a1 / 80843
• RGDID: 68321
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 476
• Identity: 425/476 - (89%)
• Similarity: 452/476 - (94%)
• Gaps: 0/476 - (0%)

  Fly     1 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWI 65
            |.|||||||||||.|||||.||||||||:|||||||||||||||||||||||||||||||||||:
  Rat     1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWM 65

  Fly    66 RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQAIV 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||:||
  Rat    66 RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQSIV 130

  Fly   131 YVMTGMYGDPSEIGAGVCLLIIIQLFAAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195
            ||||||||||||:|||:||||.||||.||||||||||||||||||||||||||||||||||||||
  Rat   131 YVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195

  Fly   196 FSPTTVTTGRGTEFEGAVIALFHLMATRNDKVRALREAFYRQNLPNLMNLLATVLVFAVVIYFQG 260
            ||||||.||||.|||||:||||||:|||.|||||||||||||||||||||:||:.||||||||||
  Rat   196 FSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQG 260

  Fly   261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFQGNFFINLLGVWA 325
            ||||||||||||||||::||||||||||||||||||||||||||||||:.:|.||..::|||.|:
  Rat   261 FRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWS 325

  Fly   326 DVGGGGPARSYPIGGLCYYLSPPESVGHILTDPIHALLYIVFMLGSCAFFSKTWIDVSGSSAKDV 390
            |...|||||:||:||||||||||||.|.:|.||:||::|||||||||||||||||:|||||||||
  Rat   326 DTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDV 390

  Fly   391 AKQLKEQHMVMRGHRENSMIHELNRYIPTAAAFGGLCIGALSVMADFLGAIGSGTGILLAVTIIY 455
            |||||||.||||||||.||:|||||||||||||||||||||||:|||||||||||||||||||||
  Rat   391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIY 455

  Fly   456 QYFEIFVKEQSEMGGMGTLLF 476
            ||||||||||||:|.||.|||
  Rat   456 QYFEIFVKEQSEVGSMGALLF 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec61alpha	NP_001285674.1	PTZ00219	1..469	CDD:185519	419/467 (90%)
Sec61a1	NP_954865.1	PTZ00219	1..471	CDD:185519	420/469 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341809
Domainoid	1	1.000	706	1.000	Domainoid score	I115
eggNOG	1	0.900	-	-		E1_COG0201
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	882	1.000	Inparanoid score	I383
OMA	1	1.010	-	-		QHG62204
OrthoDB	1	1.010	-	-		D266122at33208
OrthoFinder	1	1.000	-	-		FOG0001962
OrthoInspector	1	1.000	-	-		otm45651
orthoMCL	1	0.900	-	-		OOG6_100672
Panther	1	1.100	-	-	O	PTHR10906
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1283
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770