Protein Alignment Sec61alpha and Sec61a2

DIOPT Version :9

• Sequence 1: NP_001285674.1
• Gene: Sec61alpha / 33905
• FlyBaseID: FBgn0086357
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_067280.1
• Gene: Sec61a2 / 57743
• MGIID: 1931071
• Length: 476
• Species: Mus musculus
• Alignment Length: 476
• Identity: 434/476 - (91%)
• Similarity: 459/476 - (96%)
• Gaps: 0/476 - (0%)

  Fly     1 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWI 65
            |||||||||||||::||||.||||||||||||||||||||||||||||||||||||||||||||:
Mouse     1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWM 65

  Fly    66 RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQAIV 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||
Mouse    66 RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIV 130

  Fly   131 YVMTGMYGDPSEIGAGVCLLIIIQLFAAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195
            ||||||||||:|:|||:|||||||||.||||||||||||||||||||||||||||||||||||||
Mouse   131 YVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195

  Fly   196 FSPTTVTTGRGTEFEGAVIALFHLMATRNDKVRALREAFYRQNLPNLMNLLATVLVFAVVIYFQG 260
            |||||:.|||||||||||||||||:|||.|||||||||||||||||||||:|||.||||||||||
Mouse   196 FSPTTINTGRGTEFEGAVIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQG 260

  Fly   261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFQGNFFINLLGVWA 325
            ||||||||||||||||||||||||||||||||||||||||||||||||:|:|.|||.:||||.||
Mouse   261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLGQWA 325

  Fly   326 DVGGGGPARSYPIGGLCYYLSPPESVGHILTDPIHALLYIVFMLGSCAFFSKTWIDVSGSSAKDV 390
            ||.|||||||||:||||||||||||:|.|..||:|.::||:||||||||||||||:|||||||||
Mouse   326 DVSGGGPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDV 390

  Fly   391 AKQLKEQHMVMRGHRENSMIHELNRYIPTAAAFGGLCIGALSVMADFLGAIGSGTGILLAVTIIY 455
            |||||||.|||||||:.||:|||||||||||||||||||||||:|||||||||||||||||||||
Mouse   391 AKQLKEQQMVMRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIY 455

  Fly   456 QYFEIFVKEQSEMGGMGTLLF 476
            ||||||||||:|:||||.|.|
Mouse   456 QYFEIFVKEQAEVGGMGALFF 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec61alpha	NP_001285674.1	PTZ00219	1..469	CDD:185519	428/467 (92%)
Sec61a2	NP_067280.1	PTZ00219	1..469	CDD:185519	428/467 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838030
Domainoid	1	1.000	706	1.000	Domainoid score	I124
eggNOG	1	0.900	-	-		E1_COG0201
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38481
Inparanoid	1	1.050	882	1.000	Inparanoid score	I402
Isobase	1	0.950	-	0	Normalized mean entropy	S126
OMA	1	1.010	-	-		QHG62204
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001962
OrthoInspector	1	1.000	-	-		otm43579
orthoMCL	1	0.900	-	-		OOG6_100672
Panther	1	1.100	-	-	LDO	PTHR10906
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1289
SonicParanoid	1	1.000	-	-		X1283
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740