Protein Alignment Sec61alpha and sec61a1

DIOPT Version :9

• Sequence 1: NP_001285674.1
• Gene: Sec61alpha / 33905
• FlyBaseID: FBgn0086357
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001004801.1
• Gene: sec61a1 / 448033
• XenbaseID: XB-GENE-971480
• Length: 476
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 429/476 - (90%)
• Similarity: 455/476 - (95%)
• Gaps: 0/476 - (0%)

  Fly     1 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWI 65
            |||||||||||||:|||||.||||||||:|||||||||||||||||||||||||||||||||||:
 Frog     1 MGIKFLEVIKPFCAILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWM 65

  Fly    66 RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMVITIGQAIV 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||
 Frog    66 RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIV 130

  Fly   131 YVMTGMYGDPSEIGAGVCLLIIIQLFAAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195
            ||||||||||||:|||:||||.||||.||||||||||||||||||||||||||||||||||||||
 Frog   131 YVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKA 195

  Fly   196 FSPTTVTTGRGTEFEGAVIALFHLMATRNDKVRALREAFYRQNLPNLMNLLATVLVFAVVIYFQG 260
            ||||||.||||||||||:||||||:|||.|||||||||||||||||||||:||:.||||||||||
 Frog   196 FSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQG 260

  Fly   261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFQGNFFINLLGVWA 325
            ||||||||||||||||::||||||||||||||||||||||||||||||:.:|.||..:||||.|:
 Frog   261 FRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVNLLGTWS 325

  Fly   326 DVGGGGPARSYPIGGLCYYLSPPESVGHILTDPIHALLYIVFMLGSCAFFSKTWIDVSGSSAKDV 390
            |...|||||:||:||||||||||||.|.:|.||:||::|||||||||||||||||:|||||||||
 Frog   326 DATTGGPARAYPVGGLCYYLSPPESFGSVLDDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDV 390

  Fly   391 AKQLKEQHMVMRGHRENSMIHELNRYIPTAAAFGGLCIGALSVMADFLGAIGSGTGILLAVTIIY 455
            |||||||.||||||||.||:|||||||||||||||||||||||:|||||||||||||||||||||
 Frog   391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIY 455

  Fly   456 QYFEIFVKEQSEMGGMGTLLF 476
            ||||||||||||:|.||.|||
 Frog   456 QYFEIFVKEQSEVGSMGALLF 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec61alpha	NP_001285674.1	PTZ00219	1..469	CDD:185519	423/467 (91%)
sec61a1	NP_001004801.1	PTZ00219	1..471	CDD:185519	424/469 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	695	1.000	Domainoid score	I128
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	870	1.000	Inparanoid score	I410
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266122at33208
OrthoFinder	1	1.000	-	-		FOG0001962
OrthoInspector	1	1.000	-	-		oto104137
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1289
SonicParanoid	1	1.000	-	-		X1283
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090