DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rchy1 and Rchy1

DIOPT Version :9

Sequence 1:	NP_001260133.1	Gene:	Rchy1 / 33901	FlyBaseID:	FBgn0031816	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001007619.1	Gene:	Rchy1 / 289508	RGDID:	1359180	Length:	261	Species:	Rattus norvegicus

Alignment Length:	247	Identity:	119/247 - (48%)
Similarity:	159/247 - (64%)	Gaps:	5/247 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 GCAHYKRRAMFVTPCCNKFYKCRFCHDENETHHFDRKTLTELICSECNTRQTVREQCLNCGVRFG 247
            ||.||.|..:...|||:|.|.||.|||.:|.|..||..:.|:.|..|...|..::.|.:|...||
  Rat    19 GCEHYDRACLLKAPCCDKLYTCRLCHDTHEDHQLDRFKVKEVQCINCEKLQHAQQTCEDCSTLFG 83

  Fly   248 KYTCLICNLFDDADKQQYHCHGCGICRIGGAENFFHCEVCNMCLPIQLKIDGHRCVENISRSHCP 312
            :|.|.||:|| |.||:||||..|||||||..|:||||..||:||.:.|: ..|:|:||:||.:||
  Rat    84 EYYCSICHLF-DKDKKQYHCESCGICRIGPKEDFFHCLKCNLCLAMTLR-GKHKCIENVSRQNCP 146

  Fly   313 VCLGDIHTSRIPCHIPDCGHLLHKMCFDQLLASGHYTCPTCQTSLIDMTALWVYLDDQAERMPVP 377
            :||.||||||:..|:..||||||:.|::::|..| |.||.|..|.:|||..|..||.:..:.|:|
  Rat   147 ICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEG-YRCPLCMHSALDMTRYWRQLDIEVAQTPMP 210

  Fly   378 LKYENQRVHIFCNDCHKTSKTKFHFIGLKCVHCGAYNTTQDVKRRLSLVTDE 429
            .:|:|..|.|.||||:..|..:||.:|:||..|.:|||.|...|.:|:  ||
  Rat   211 SEYQNVTVDILCNDCNGRSTVQFHILGMKCKLCDSYNTAQAGGRTVSM--DE 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rchy1	NP_001260133.1	zf-CHY	184..257	CDD:283213	30/72 (42%)
		RING	311..357	CDD:238093	24/45 (53%)
		zinc_ribbon_6	358..416	CDD:291274	25/57 (44%)
Rchy1	NP_001007619.1	zf-CHY	20..93	CDD:283213	30/72 (42%)
		zf-RING_2	144..186	CDD:290367	22/41 (54%)
		zinc_ribbon_6	191..249	CDD:291274	24/57 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8347
eggNOG	1	0.900	-	-		E1_KOG1940
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H22894
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2905
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002942
OrthoInspector	1	1.000	-	-		oto97546
orthoMCL	1	0.900	-	-		OOG6_101709
Panther	1	1.100	-	-	LDO	PTHR21319
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1699
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.820