DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rchy1 and SPAC2F3.16

DIOPT Version :9

Sequence 1:	NP_001260133.1	Gene:	Rchy1 / 33901	FlyBaseID:	FBgn0031816	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_594394.1	Gene:	SPAC2F3.16 / 2541608	PomBaseID:	SPAC2F3.16	Length:	425	Species:	Schizosaccharomyces pombe

Alignment Length:	236	Identity:	88/236 - (37%)
Similarity:	133/236 - (56%)	Gaps:	5/236 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 GCAHYKRRAMFVTPCCNKFYKCRFCHDENETHHFDRKTLTELICSECNTRQTVREQCLNCGVRFG 247
            ||:||.|........|:::|.||.||::...|..:|..:..::|..|:..|...:.|..|....|
pombe   141 GCSHYMRNCKVQCFDCHEWYTCRHCHNDACDHVLERPAVENMLCMICSKVQPAAQYCKYCKNCMG 205

  Fly   248 KYTCLICNLF-DDADKQQYHCHGCGICRIGG--AENFFHCEVCNMCLPIQLKIDGHRCVENISRS 309
            :|.|..|.|: ||.:|..|||..|||||||.  .:::|||:.|.:||||.: .:.|||:|..:..
pombe   206 RYYCNKCKLWDDDPNKSSYHCDDCGICRIGRGLGDDYFHCKTCGLCLPISV-FNTHRCIERSTDC 269

  Fly   310 HCPVCLGDIHTSRIPCHIPDCGHLLHKMCFDQLLASGHYTCPTCQTSLIDMTALWVYLDDQAERM 374
            :||:|...:..||.......|.|.||:.|.::.:.: :|.||||..::|::.:|:..||.:.||.
pombe   270 NCPICGEYMFNSRERVIFLSCSHPLHQRCHEEYIRT-NYRCPTCYKTIINVNSLFRILDMEIERQ 333

  Fly   375 PVPLKYENQRVHIFCNDCHKTSKTKFHFIGLKCVHCGAYNT 415
            |:|..|......|.||||:....||:||:|.||..|.:|||
pombe   334 PMPYPYNTWISTIRCNDCNSRCDTKYHFLGHKCNSCHSYNT 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rchy1	NP_001260133.1	zf-CHY	184..257	CDD:283213	21/72 (29%)
		RING	311..357	CDD:238093	15/45 (33%)
		zinc_ribbon_6	358..416	CDD:291274	25/58 (43%)
SPAC2F3.16	NP_594394.1	zf-CHY	142..215	CDD:283213	21/72 (29%)
		zf-RING_2	270..312	CDD:290367	13/42 (31%)
		zinc_ribbon_6	317..375	CDD:291274	25/58 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	55	1.000	Domainoid score	I3206
eggNOG	1	0.900	-	-		E1_KOG1940
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I1052
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002942
OrthoInspector	1	1.000	-	-		oto101492
orthoMCL	1	0.900	-	-		OOG6_101709
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1810
SonicParanoid	1	1.000	-	-		X1699
TreeFam	1	0.960	-	-
	10	9.750