DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frj and mboat2b

DIOPT Version :9

Sequence 1:	NP_609029.1	Gene:	frj / 33900	FlyBaseID:	FBgn0031815	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001265531.1	Gene:	mboat2b / 692278	ZFINID:	ZDB-GENE-041001-185	Length:	498	Species:	Danio rerio

Alignment Length:	489	Identity:	114/489 - (23%)
Similarity:	199/489 - (40%)	Gaps:	98/489 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSIDDVIYVICLLGCIGAGSYVKKIADEGQ-----RKLVSTGLGVLVVVIVSGLHSLHCFVSLAL 60
            :.:|.|.:|:|.|..:....:.:......:     |.:|:|.||:...:...|.::||..:...:
Zfish    24 LPLDQVNFVVCQLCALLTAVWFRLYLHPSKTSPFVRHVVATLLGIYFALFCFGWYALHFLLQSGI 88

  Fly    61 GTAAVLLVHPSKGHLVTFAVMFGYLVF---FRIFDFYFGI-------PGHTNMIQMILTLKVSGI 115
            ....::|......|.....|..|||.|   .|::.|.:|:       |      .|::|.|::.:
Zfish    89 TYGIMILTGVEHMHKYCLVVALGYLSFCQITRVYVFDYGMYSADFTGP------MMVITQKITSV 147

  Fly   116 AFEKTAAWKRLQAHDEQKKNDQRDVHQESPIEITDYDVELQSL----SAAEILHYSFNYIGVLTG 176
            |||         .||...:.          :|..:...:|.::    |..|...|:.|::|:|.|
Zfish   148 AFE---------IHDGMARK----------VEQLNQGQKLLAIRRMPSLLEYFSYNCNFMGILAG 193

  Fly   177 PYYRYRTYRDYFE-MPFK-----------------TYAPTVEATLEKLKYAVFYCALYLATNYMW 223
            |...|..|..:.| .|::                 ..:|..| .:.||........::|:...::
Zfish   194 PTCSYNDYIAFIEGTPYRHRDLEPKGKVNGKSRLNDPSPNTE-VIRKLSTCFISLLVFLSVCKVF 257

  Fly   224 PLDYALSDEFFNDRSFVYRLLYVWPTFFTFRARIYTGLTLSECVCTMAGFGAYPDESDPNNGEGP 288
            |::..:.|:|.....|..:::|::.:..|.|.:.|...||::.:...||||....:||.:    |
Zfish   258 PVERNVDDDFIATSPFYVQVVYLYLSMLTTRPKYYFVWTLADAINNAAGFGFNGYDSDGS----P 318

  Fly   289 RKRYQHLKRDADKHTYNFTTIVNTRVLEVERCWTFREGMKHWNVCVQYWLAVNVYKLFPSKKYRT 353
            |                :..:.|.|:|.:|...:|:..:.:||:...:||....|:..|...  |
Zfish   319 R----------------WDLLSNIRILNIELATSFKVFLDNWNIQTAHWLKRVCYERCPYNP--T 365

  Fly   354 GATLLCSAYWHGFRPGHYFCIMGAPFYVSLEDMWDKLVRKS------ATGTSRRVIDVIFWIFKW 412
            .||.|.||.|||..||:|...: ....::|.   .:.||.:      .:.:.:.|.|||.|....
Zfish   366 AATFLLSAMWHGAYPGYYLTFL-TGIVITLA---ARAVRHNVRPHFLGSPSHKFVYDVITWAATQ 426

  Fly   413 FAFSYLGEAFLLSSFGNIWRFYSSVY---HIGYI 443
            .|..|....|:|.|.|...:||.|.|   |||.|
Zfish   427 IAICYTVVPFVLLSVGPSLKFYRSWYFCLHIGCI 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frj	NP_609029.1	MBOAT	93..427	CDD:281107	83/368 (23%)
mboat2b	NP_001265531.1	MBOAT	15..470	CDD:294479	114/489 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920