DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frj and Mboat7

DIOPT Version :9

Sequence 1:	NP_609029.1	Gene:	frj / 33900	FlyBaseID:	FBgn0031815	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001128450.2	Gene:	Mboat7 / 308309	RGDID:	1306945	Length:	473	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	155/486 - (31%)
Similarity:	246/486 - (50%)	Gaps:	31/486 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSIDDVIYVICLLGCIGAGSYVKKIADEGQRKLVSTGLGVLVVVIVSGLHSLHCFVSLALGTAAV 65
            |:.::..|::.||..|..|...|| |..|.::..:..:|:.:.:...|.||||..::: |||.|:
  Rat     1 MTPEEWTYLMVLLISIPVGFLFKK-AGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITI-LGTWAL 63

  Fly    66 LLVHPSKGHLVTFAVMFGYLVFFRIFDFYFGIP---GHTNMIQMILTLKVSGIAFEKTAAWKRLQ 127
            :...|...|.:..|..|.||:|||.... .|:|   ..||.:|::||||:..:|.|..      .
  Rat    64 IQAQPCSCHALALAWTFSYLLFFRALSL-LGLPTPTPFTNAVQLLLTLKLVSLASEVQ------D 121

  Fly   128 AHDEQKKNDQRDVHQESPIEITDYDVELQSLSAAEILHYSFNYIGVLTGPYYRYRTYRDYFEMPF 192
            .|..|:|.......:|..:.:.. ||.    |..|.|.||:.|:|::|||::|||||.|:.|.||
  Rat   122 LHLAQRKEMASGFSKEPTLGLLP-DVP----SLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPF 181

  Fly   193 KTYAPTVEATLEKLKYAVFYCALYLATNYMWPLDYALSDEFFNDRSFVYRLLYVWPTFFTFRARI 257
            ....|::...|.:...|..:..|:|.:::::||: |:.::.|..|....||.|:.|.||.||.|.
  Rat   182 PEAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLE-AVREDAFYARPLPTRLFYMIPVFFAFRMRF 245

  Fly   258 YTGLTLSECVCTMAGFGAYPDESDPNNGEGPRKRY--QHLKRDADKHTYNFTTIVNTRVLEVERC 320
            |.....:||.|..|||||||..:....|.||..:.  ......|....|::..|.|......:.|
  Rat   246 YVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYEAIRNIDCYGTDFC 310

  Fly   321 WTFREGMKHWNVCVQYWLAVNVYKLFPSKKY--RTGATLLCSAYWHGFRPGHYFCIMGAPFYVSL 383
            ...|:||::||:.||:|||..:||..|.:.|  |:..|:|.||||||..||:|...|..|..::.
  Rat   311 VRVRDGMRYWNMTVQWWLAQYIYKSAPFRSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCLAA 375

  Fly   384 EDMWDKLVRKSATGTSRRVIDVIFWIFKWFAFSYLGEAFLLSSFGNIWRFYSSVYHIGYISWAAM 448
            |...:..:|:..:...::..|...|..|..|:.|:...|:|.|.|:..|:::|:|.  ::.:.|:
  Rat   376 EGYLESALRRHLSPGGQKAWDWFHWFLKMRAYDYMCMGFVLLSMGDTLRYWASIYF--WVHFLAL 438

  Fly   449 TALGFYLT------SQRKA-AERRKKRAAEK 472
            ..||..|.      |:||. ::....:|.||
  Rat   439 ACLGLGLALGGGSPSKRKTPSQATTSQAKEK 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frj	NP_609029.1	MBOAT	93..427	CDD:281107	111/340 (33%)
Mboat7	NP_001128450.2	MBOAT	8..431	CDD:382173	143/437 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338775
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H11510
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D475957at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940